Protein Alignment Socs44A and SOCS2

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: XP_016875636.1
• Gene: SOCS2 / 8835
• HGNCID: 19382
• Length: 243
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 50/198 - (25%)
• Similarity: 89/198 - (44%)
• Gaps: 34/198 - (17%)

  Fly   161 RKKWLEREDAHSPN---QIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQ 222
            |.:|.....|..|:   ..:.||..|:....||||.::..:::.:|.:.|.|:||:|||..|...
Human    17 RSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYL 81

  Fly   223 FTLSFRIVNVTLHYRLEYRDNFWHFEEL--------KYESIVEMIEDILHRCTNDNFVCFVKVPN 279
            .|:|.:......:.|:||:|..:..:.:        :::|:|.:|:..:..|.:          .
Human    82 LTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKD----------K 136

  Fly   280 EMQPPFP------VILKYPLSRYSNMPKLQDLCRRVLQRQMSREQLAQLPVPAQMLEYLSVEREL 338
            ...|..|      :.|..||  |::.|.||.|||..:.:  ....:..||:|.::.:||   .|.
Human   137 RTGPEAPRNGTVHLYLTKPL--YTSAPSLQHLCRLTINK--CTGAIWGLPLPTRLKDYL---EEY 194

  Fly   339 VFQ 341
            .||
Human   195 KFQ 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	22/85 (26%)
		SOCS	293..333	CDD:470605	12/39 (31%)
SOCS2	XP_016875636.1	SH2_SOCS2	40..142	CDD:198246	25/111 (23%)
		SOCS_SOCS2	158..198	CDD:239705	14/45 (31%)