Protein Alignment Socs44A and Cish

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_113992.1
• Gene: Cish / 83681
• RGDID: 69261
• Length: 257
• Species: Rattus norvegicus
• Alignment Length: 238
• Identity: 63/238 - (26%)
• Similarity: 97/238 - (40%)
• Gaps: 51/238 - (21%)

  Fly   142 PAICPEPTLPFTHDYLRFIRKKWLEREDAHSPNQ-----------IMYKACSEMLNQVWYWGEIS 195
            ||:.|.||..|..:.        .|.....|.|:           .:.|..|.:....||||.|:
  Rat    32 PAMQPLPTGAFPEEV--------TEETPVQSENEPKVLDPEGDLLCIAKTFSYLRESGWYWGSIT 88

  Fly   196 RRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFWHFEE--------LKY 252
            ..::::.|...|.|:||||||......||||.:......:.|:||.|:.:..:.        |.:
  Rat    89 ASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAF 153

  Fly   253 ESIVEMIEDILHRCTNDNF--------VCFVKVPNEMQPPFPVI-----------LKYPLSRYSN 298
            ..:|.:::..:..||.|..        ...:.||....|..||:           |..|..|.|:
  Rat   154 PDVVSLVQHYVASCTADTRSDSPDPAPTPALPVPKPDAPGDPVLPIPVATAVHLKLVQPFVRRSS 218

  Fly   299 MPKLQDLCRRVLQRQMSREQLAQLPVPAQMLEYLSVERELVFQ 341
            ...||.|||.|:.|.::  .:..||:|.:|.:||   |:..||
  Rat   219 ARSLQHLCRLVINRLVT--DVDCLPLPRRMADYL---RQYPFQ 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	24/85 (28%)
		SOCS	293..333	CDD:470605	14/39 (36%)
Cish	NP_113992.1	SH2_CIS	77..164	CDD:198285	24/86 (28%)
		SOCS_CIS1	217..257	CDD:239703	17/45 (38%)