Protein Alignment Socs44A and socs4

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: XP_021322920.1
• Gene: socs4 / 797891
• ZFINID: ZDB-GENE-070720-4
• Length: 423
• Species: Danio rerio
• Alignment Length: 419
• Identity: 95/419 - (22%)
• Similarity: 145/419 - (34%)
• Gaps: 142/419 - (33%)

  Fly    15 SQALTGGGDSPRDREKEKKGWFHSLTRRK--KSDSALAVTASAAVSTSGSQN----NNNEVCVLE 73
            |:||.|.|.......|.|    :|.||.|  :|.||.:...|....:.||::    ...|....:
Zfish    33 SEALFGKGPEAMSERKTK----NSDTRPKNLRSWSADSYIRSIKKRSRGSRHETAPRGEEGDGAD 93

  Fly    74 AADSSMASCSNGGTGTGTLRRRR------------DKDK--RNVFAR--LRRK----VGQGLSSL 118
            ...:..|||.         ||||            |.|.  |...:|  ||:|    |||.| .|
Zfish    94 EQTARSASCP---------RRRRERMCSCTIPGETDSDSPCRKALSRRSLRQKFQDAVGQCL-PL 148

  Fly   119 RNWH---------------------------------------SMGDC-----DDGGTTDATYEF 139
            ||.|                                       .:..|     ..|..|..:...
Zfish   149 RNHHHHHHHPSGSSRPFSVLLWSKRKIHVSELMEDKCPFSPKSELAQCWHLIKKHGTNTKPSLSI 213

  Fly   140 LT----PAICPEPTLPFTHDYLRFIRKKWLERED-----------AHSPNQIMYKACSEMLNQVW 189
            .|    |.:...|....:.:.:.......|:..|           ||: :.|:.....::.|...
Zfish   214 ETEPKGPLLSSTPPTLLSWEQIGSTGASSLDDWDPSFALGDSQCCAHT-DYILVPDLLQINNSPC 277

  Fly   190 YWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLE--------------- 239
            |||.:.|.::::.|..:|.|:||:|||......|::|||..:.:||.|:|
Zfish   278 YWGVLDRFEAEQLLEGQPEGTFLLRDSAQDEYLFSVSFRRYSRSLHARIEQNGKRFSFDGRDPCM 342

  Fly   240 YRDNFWHFEELKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQPPFPVILKYPLSRYSNMP-KLQ 303
            |||:          |:..:::..     :|...|..         |..:|..||.|  |.| .||
Zfish   343 YRDS----------SVTGLLKHY-----SDPSTCLF---------FEPLLSRPLPR--NFPFSLQ 381

  Fly   304 DLCRRVLQRQMSREQLAQLPVPAQMLEYL 332
            .|||.|:....:.:.:..||:|..:..:|
Zfish   382 HLCRAVICSCTTYQGIEALPLPYTLRHFL 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	24/92 (26%)
		SOCS	293..333	CDD:470605	14/41 (34%)
socs4	XP_021322920.1	SOCS	100..150	CDD:432667	19/59 (32%)
		SH2	266..366	CDD:472789	28/123 (23%)
		SOCS	376..>416	CDD:470605	11/35 (31%)