Protein Alignment Socs44A and Socs4

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_543119.2
• Gene: Socs4 / 67296
• MGIID: 1914546
• Length: 436
• Species: Mus musculus
• Alignment Length: 329
• Identity: 83/329 - (25%)
• Similarity: 132/329 - (40%)
• Gaps: 84/329 - (25%)

  Fly    24 SPRDREKEKKGWFHS-LTRRKKSDSALAVTASAAVSTSGSQNNNNEVCVLEAADSSMASCSNGGT 87
            ||...|     |..: |:.||..|:.|. ..:.........:.|.:.||:.|   :.|||: ||.
Mouse   152 SPNSDE-----WVSADLSERKLRDAQLK-RRNTEDDIPCFSHTNGQPCVITA---NSASCT-GGH 206

  Fly    88 GTGTLRRRRDKDKRNVFARLRRKVGQGLSSLRNWHSMGDCDDGGTTDATYEFLTPAICPEPTLPF 152
            .||::                      ::.:.| :|:.|.|    .|:..|.:|  :|...
Mouse   207 ITGSM----------------------MNLVTN-NSIEDSD----MDSEDEIIT--LCTSS---- 238

  Fly   153 THDYLRFIRK----KW-LERE--DAHSP----NQIMYKAC-----SEMLNQVWYWGEISRRDSQR 201
                    ||    :| :|.|  ...:|    .||.|..|     .::.|...|||.:.:..::.
Mouse   239 --------RKRNKPRWEMEEEILQLEAPPKFHTQIDYVHCLVPDLLQISNNPCYWGVMDKYAAEA 295

  Fly   202 QLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFWHFEELKYESIVEMIEDI--LH 264
            .|..||.|:||:|||......|::|||..:.:||.|:|..::.:.|:  .::..|....||  |.
Mouse   296 LLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFD--AHDPCVFHSPDITGLL 358

  Fly   265 RCTNDNFVCFVKVPNEMQPPFPVILKYPLSRYSNMP-KLQDLCRRVLQRQMSREQLAQLPVPAQM 328
            ....|...|..         |..:|..||.|  ..| .||.:||.|:....:.:.:..||:|:.|
Mouse   359 EHYKDPSACMF---------FEPLLSTPLIR--TFPFSLQHICRTVICNCTTYDGIDALPIPSPM 412

  Fly   329 LEYL 332
            ..||
Mouse   413 KLYL 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	25/79 (32%)
		SOCS	293..333	CDD:470605	14/41 (34%)
Socs4	NP_543119.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		SOCS	55..106	CDD:432667
		SH2_SOCS4	272..372	CDD:198248	29/110 (26%)
		SOCS_SOCS4	381..436	CDD:239707	12/36 (33%)