Protein Alignment Socs44A and Socs6

DIOPT Version :9

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_061291.2
• Gene: Socs6 / 54607
• MGIID: 1924885
• Length: 533
• Species: Mus musculus
• Alignment Length: 239
• Identity: 72/239 - (30%)
• Similarity: 107/239 - (44%)
• Gaps: 46/239 - (19%)

  Fly   130 GGTTDATYEFLTPAICPEPTLPFTHDYLRFIRKKWLEREDAH-----------SPNQI------- 176
            ||..||..  |:|.:.|....|...::      ..|...|.|           .||..
Mouse   300 GGHDDAPP--LSPLLPPMQNNPIQRNF------SGLSGPDLHMAESVRCHLNFDPNSAPGVARVY 356

  Fly   177 -------------MYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFR 228
                         :.:...::..|.||||.|:|.:::.:|::.|.||||||||.......:||||
Mouse   357 DSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFR 421

  Fly   229 IVNVTLHYRLEYRDNFWHFEELK----YESIVEMIEDILHRCTNDNFVCFVKVPNEMQPPFPVIL 289
            ....|||.|:|:.:..:.|.|..    :.|||::||..:....|..| |:.:........:||.|
Mouse   422 SHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAF-CYSRSRLPGSATYPVRL 485

  Fly   290 KYPLSRYSNMPKLQDLCRRVLQRQMSREQLAQ-LPVPAQMLEYL 332
            ..|:||:..:..||.|||.|: ||.:|..|.| ||:|.:|.:||
Mouse   486 TNPVSRFMQVRSLQYLCRFVI-RQYTRIDLIQKLPLPNKMKDYL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	32/81 (40%)
		SOCS	293..333	CDD:295349	19/41 (46%)
Socs6	NP_061291.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..136
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..199
		SH2_SOCS6	371..470	CDD:198250	35/99 (35%)
		SOCS_SOCS6	493..533	CDD:239709	17/37 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3554
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770