Protein Alignment Socs44A and Sla2

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001165589.1
• Gene: Sla2 / 499931
• RGDID: 1562071
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 321
• Identity: 69/321 - (21%)
• Similarity: 115/321 - (35%)
• Gaps: 88/321 - (27%)

  Fly    38 SLTRRKKSDSALAVTASAAVSTSGSQNNNNEVCVLEAADSSMASCSNGGTGTGTLRRRRDKDKRN 102
            ||..|.|:.|     .|::.|.||.   ..|...::|....:::.:.|....|..
  Rat     4 SLPSRGKNSS-----PSSSSSFSGP---GQEPVSIQAERQKVSAVALGSFPAGEQ---------- 50

  Fly   103 VFARLRRKVGQGLSSLRNWHSMGDCDDGGTTDATYEFLTPAICPEPTLPFTHDYLRFIRKKWLER 167
              |||..:||:.|:.:        .:||.......|                          :..
  Rat    51 --ARLSLRVGEPLTII--------SEDGDWWTVQSE--------------------------VSG 79

  Fly   168 EDAHSPNQIMYKACSEMLNQVWYWGEISRRDSQR--QLSDKPTGSFLVRDSETSGSQFTLSFRIV 230
            .:.|.|:..:.|     ::..|.:..:||..::.  .|...|.|:||:|:|:|....::||.|:.
  Rat    80 REYHIPSVYVAK-----VSHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGCYSLSIRLS 139

  Fly   231 NVT-----LHYRLEYRDNFWHF--EELKYESIVEMIEDILHRCTNDNFVCFVKVPNEMQ------ 282
            ...     .|||::..||.|.:  ..|.:.|:..::|......  |...|.::.|..:|
  Rat   140 RPASWDRIRHYRIQRLDNGWLYISPRLTFPSLHALVEHYSELA--DGICCALREPCVLQKLGPLP 202

  Fly   283 ---PPFPVILKYPLSRYSNMPKLQD--LCRRVLQRQMSRE-QLAQLPVPAQMLEYLSVERE 337
               .|.||.:  |.|.. |..||..  ||   |....|.| .|....:...:..|:|:..|
  Rat   203 GKDTPLPVTV--PTSSL-NWKKLDRSLLC---LDAPASGEASLLSEGLRESLSSYISLTEE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	23/86 (27%)
		SOCS	293..333	CDD:470605	11/42 (26%)
Sla2	NP_001165589.1	SH3	39..92	CDD:473055	14/103 (14%)
		SH2_SLAP	85..187	CDD:198207	26/108 (24%)