DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs44A and socs1a

DIOPT Version :9

Sequence 1:	NP_523659.1	Gene:	Socs44A / 35786	FlyBaseID:	FBgn0033266	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001003467.1	Gene:	socs1a / 445073	ZFINID:	ZDB-GENE-040801-205	Length:	201	Species:	Danio rerio

Alignment Length:	162	Identity:	34/162 - (20%)
Similarity:	75/162 - (46%)	Gaps:	26/162 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 QIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLE 239
            :|:....|.:....:|||.::..::..:|..:..|:||:|||..|...||||::..|..:..|:.
Zfish    55 KIISNTTSMLEESGFYWGPMTVEEAHLKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRIN 119

  Fly   240 YRDNFWHFEELK--YESIVEMIEDILHRCTNDNFVCFVKVPNE--MQPPFPVILKYPLSRYSNMP 300
            ::::.:.....|  ::|:.:::|.            ::..|.:  ::|          .|...:.
Zfish   120 FKNSKFSLTGSKESFDSLFKLLEH------------YISSPKKGLIRP----------CRKEPVQ 162

  Fly   301 KLQDLCRRVLQRQMSREQLAQLPVPAQMLEYL 332
            .||.||||.:..:...:.:..:||...:.::|
Zfish   163 SLQQLCRRQIMERCDGKDIDCIPVQPILKDFL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	20/79 (25%)
Socs44A	NP_523659.1	SOCS	293..333	CDD:295349	10/40 (25%)
socs1a	NP_001003467.1	SH2_SOCS1	58..155	CDD:198245	22/108 (20%)
socs1a	NP_001003467.1	SOCS	161..198	CDD:295349	9/34 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740