Protein Alignment Socs44A and SOCS7

DIOPT Version :9

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_055413.2
• Gene: SOCS7 / 30837
• HGNCID: 29846
• Length: 645
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 105/411 - (25%)
• Similarity: 156/411 - (37%)
• Gaps: 116/411 - (28%)

  Fly     1 MSHGDQSQNQSSQ-------------------------------RSQAL---TGGGDSPRDREKE 31
            :|.|:|.|.|..|                               |:::.   :||||.
Human   239 LSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDG------- 296

  Fly    32 KKGWFHSLTRRKKSDSALAVTASAAVSTSGSQNNNNEV---CVLEAADSSMASCSNGGTGTGTLR 93
                     ..|:....||.:|::.....||.....:.   ..|....|:.:..|.....||...
Human   297 ---------TGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETV 352

  Fly    94 RRRDKDKRNVFARLRRKVGQ-GLSSLRNWH----------SMGDCDDGGTTDATYEFLTPAIC-- 145
            ...|.|           :.| ||:|.   |          |:...||...|..|...:.|...
Human   353 SLVDVD-----------ISQRGLTSP---HPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSL 403

  Fly   146 --------PEPTLPFTHDYLRFIRKKWLEREDAHS------------PNQIMYKACSEMLNQV-W 189
                    |.|..|.....:..||    ..|..||            |:...:.|....|.:. |
Human   404 QSFPLPPPPPPHAPDAFPRIAPIR----AAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGW 464

  Fly   190 YWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLE-YRDNF--W---HFE 248
            |||.::..|::.:|..||.||||||||.......:||||...:|.|.|:| ||..|  |   .||
Human   465 YWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFE 529

  Fly   249 ELKYESIVEMIEDILHRCTNDNFVCFV--KVPNEMQPPFPVILKYPLSRYSNMPKLQDLCRRVLQ 311
            : :.:|:||.|:..:....|..|:.|:  :||.  .||.||.|.||:||:||:..||.|||..::
Human   530 D-RCQSVVEFIKRAIMHSKNGKFLYFLRSRVPG--LPPTPVQLLYPVSRFSNVKSLQHLCRFRIR 591

  Fly   312 RQMSREQLAQLPVPAQMLEYL 332
            :.:..:.:..||:|..::.|:
Human   592 QLVRIDHIPDLPLPKPLISYI 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	34/84 (40%)
		SOCS	293..333	CDD:295349	13/40 (33%)
SOCS7	NP_055413.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10155
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3554
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940