Protein Alignment Socs44A and Socs6

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001258078.1
• Gene: Socs6 / 307200
• RGDID: 1304632
• Length: 547
• Species: Rattus norvegicus
• Alignment Length: 239
• Identity: 72/239 - (30%)
• Similarity: 107/239 - (44%)
• Gaps: 46/239 - (19%)

  Fly   130 GGTTDATYEFLTPAICPEPTLPFTHDYLRFIRKKWLEREDAH-----------SPNQI------- 176
            ||..||..  |:|.:.|....|...::      ..|...|.|           .||..
  Rat   314 GGHDDAPP--LSPLLPPMQNNPIQRNF------SGLSGPDLHMAESVRCHLNFDPNSAPGVARVY 370

  Fly   177 -------------MYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFR 228
                         :.:...::..|.||||.|:|.:::.:|::.|.||||||||.......:||||
  Rat   371 DSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFR 435

  Fly   229 IVNVTLHYRLEYRDNFWHFEELK----YESIVEMIEDILHRCTNDNFVCFVKVPNEMQPPFPVIL 289
            ....|||.|:|:.:..:.|.|..    :.|||::||..:....|..| |:.:........:||.|
  Rat   436 SHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAF-CYSRSRLPGSATYPVRL 499

  Fly   290 KYPLSRYSNMPKLQDLCRRVLQRQMSREQLAQ-LPVPAQMLEYL 332
            ..|:||:..:..||.|||.|: ||.:|..|.| ||:|.:|.:||
  Rat   500 TNPVSRFMQVRSLQYLCRFVI-RQYTRIDLIQKLPLPNKMKDYL 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	32/81 (40%)
		SOCS	293..333	CDD:470605	19/41 (46%)
Socs6	NP_001258078.1	SH2_SOCS6	385..484	CDD:198250	35/99 (35%)
		SOCS_SOCS6	507..547	CDD:239709	17/37 (46%)