DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs44A and Socs7

DIOPT Version :9

Sequence 1:	NP_523659.1	Gene:	Socs44A / 35786	FlyBaseID:	FBgn0033266	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	XP_006247546.3	Gene:	Socs7 / 287659	RGDID:	1307720	Length:	642	Species:	Rattus norvegicus

Alignment Length:	208	Identity:	70/208 - (33%)
Similarity:	104/208 - (50%)	Gaps:	28/208 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 PEPTLPFTHDYLRFIRKKWLEREDAHS------------PNQIMYKACSEMLNQV-WYWGEISRR 197
            |.|..|.....:..||..    |..||            |:...:.|....|.:. ||||.::..
  Rat   409 PPPHAPDAFPRIAPIRAS----ESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWE 469

  Fly   198 DSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLE-YRDNF--W---HFEELKYESIV 256
            |::.:|..||.||||||||.......:||||...:|.|.|:| ||..|  |   .||: :.:|:|
  Rat   470 DAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFED-RCQSVV 533

  Fly   257 EMIEDILHRCTNDNFVCFV--KVPNEMQPPFPVILKYPLSRYSNMPKLQDLCRRVLQRQMSREQL 319
            |.|:..:....|..|:.|:  :||.  .||.||.|.||:||:||:..||.|||..:::.:..:.:
  Rat   534 EFIKRAIMHSKNGKFLYFLRSRVPG--LPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHI 596

  Fly   320 AQLPVPAQMLEYL 332
            ..||:|..::.|:
  Rat   597 PDLPLPKPLISYI 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	34/84 (40%)
Socs44A	NP_523659.1	SOCS	293..333	CDD:295349	13/40 (33%)
Socs7	XP_006247546.3	SH2_SOCS7	450..550	CDD:198251	38/100 (38%)
Socs7	XP_006247546.3	SOCS_SOCS7	574..622	CDD:239710	11/36 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10155
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010