Protein Alignment Socs44A and Socs7

DIOPT Version :10

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_619598.2
• Gene: Socs7 / 192157
• MGIID: 2651588
• Length: 648
• Species: Mus musculus
• Alignment Length: 208
• Identity: 70/208 - (33%)
• Similarity: 104/208 - (50%)
• Gaps: 28/208 - (13%)

  Fly   146 PEPTLPFTHDYLRFIRKKWLEREDAHS------------PNQIMYKACSEMLNQV-WYWGEISRR 197
            |.|..|.....:..||..    |..||            |:...:.|....|.:. ||||.::..
Mouse   415 PPPHAPDAFPRIAPIRAS----ESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWE 475

  Fly   198 DSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLE-YRDNF--W---HFEELKYESIV 256
            |::.:|..||.||||||||.......:||||...:|.|.|:| ||..|  |   .||: :.:|:|
Mouse   476 DAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFED-RCQSVV 539

  Fly   257 EMIEDILHRCTNDNFVCFV--KVPNEMQPPFPVILKYPLSRYSNMPKLQDLCRRVLQRQMSREQL 319
            |.|:..:....|..|:.|:  :||.  .||.||.|.||:||:||:..||.|||..:::.:..:.:
Mouse   540 EFIKRAIMHSKNGKFLYFLRSRVPG--LPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHI 602

  Fly   320 AQLPVPAQMLEYL 332
            ..||:|..::.|:
Mouse   603 PDLPLPKPLISYI 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	34/84 (40%)
		SOCS	293..333	CDD:470605	13/40 (33%)
Socs7	NP_619598.2	SH2_SOCS7	456..556	CDD:198251	38/100 (38%)
		SOCS_SOCS7	580..628	CDD:239710	11/36 (31%)