DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs44A and F39B2.5

DIOPT Version :9

Sequence 1:	NP_523659.1	Gene:	Socs44A / 35786	FlyBaseID:	FBgn0033266	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_493574.2	Gene:	F39B2.5 / 185487	WormBaseID:	WBGene00009556	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	167	Identity:	47/167 - (28%)
Similarity:	83/167 - (49%)	Gaps:	9/167 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 CSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFW 245
            ||::.:..||||::..:.::|.|...|.|.||:|||.:....||:|:...:...|.||...|:..
Worm     8 CSDLYDCDWYWGDLDWKWAERLLLLCPIGYFLIRDSRSETHLFTVSYHFQDRVYHSRLSLEDSRR 72

  Fly   246 H------FEELKYESIVEMIEDILHR-CTNDNFVCFVKVPNEMQPPFPVILKYPLSRYSNMPKLQ 303
            :      :....|.::||:||..|.: .|....:...:..:|.:.. .|.|..||::...:|.||
Worm    73 NLGSRQPYVSRDYWNLVEIIERSLEQSLTGQQEMLHYRRGHEAEAA-RVNLTRPLTKRELLPSLQ 136

  Fly   304 DLCRRVLQRQMSREQLAQ-LPVPAQMLEYLSVERELV 339
            .|||..|:....:....: .|:|..:|:|||..:.::
Worm   137 YLCRFTLKTSQQKPPTPKTAPLPPTILKYLSDSKWII 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	26/84 (31%)
Socs44A	NP_523659.1	SOCS	293..333	CDD:295349	12/40 (30%)
F39B2.5	NP_493574.2	SH2_SOCS7	5..106	CDD:198251	29/97 (30%)
F39B2.5	NP_493574.2	SOCS	126..169	CDD:128549	14/42 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6278
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3554
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.790