Protein Alignment Socs44A and Socs1

DIOPT Version :9

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001258532.1
• Gene: Socs1 / 12703
• MGIID: 1354910
• Length: 212
• Species: Mus musculus
• Alignment Length: 202
• Identity: 52/202 - (25%)
• Similarity: 85/202 - (42%)
• Gaps: 49/202 - (24%)

  Fly   142 PAICPEPTLPFTH--------DYLRFIRKKWLEREDAHSPNQIMYKACSEMLNQVWYWGEISRRD 198
            ||: |.|....||        ||.|..|            ...:..||.      :|||.:|...
Mouse    44 PAV-PAPAPGDTHFRTFRSHSDYRRITR------------TSALLDACG------FYWGPLSVHG 89

  Fly   199 SQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFWHFEELK--YESIVEMIED 261
            :..:|..:|.|:||||||......|.||.::.:.....|:.::...:|.:..:  ::.:.|::|.
Mouse    90 AHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRETFDCLFELLEH 154

  Fly   262 ILHRCTNDNFVCFVKVPNEMQPPFPVILKYPLSRYSNMPKLQDLCRRVLQRQMSREQLAQLPVPA 326
                        :|..|..|       |..|| |...:..||:|||:.:...:.||.||::|:..
Mouse   155 ------------YVAAPRRM-------LGAPL-RQRRVRPLQELCRQRIVAAVGRENLARIPLNP 199

  Fly   327 QMLEYLS 333
            .:.:|||
Mouse   200 VLRDYLS 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	20/79 (25%)
		SOCS	293..333	CDD:295349	13/39 (33%)
Socs1	NP_001258532.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		4/11 (36%)
		Kinase inhibitory region (KIR)	56..67		2/10 (20%)
		Extended SH2 subdomain (ESS)	68..79		2/22 (9%)
		SH2_SOCS1	69..166	CDD:198245	27/133 (20%)
		SOCS	170..212	CDD:295349	13/37 (35%)
		Interaction with Elongin BC complex	174..183		5/8 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833074
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6278
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.690