Protein Alignment Socs44A and Cish

DIOPT Version :9

• Sequence 1: NP_523659.1
• Gene: Socs44A / 35786
• FlyBaseID: FBgn0033266
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: XP_006511698.1
• Gene: Cish / 12700
• MGIID: 103159
• Length: 325
• Species: Mus musculus
• Alignment Length: 238
• Identity: 60/238 - (25%)
• Similarity: 96/238 - (40%)
• Gaps: 51/238 - (21%)

  Fly   142 PAICPEPTLPFTHDYLRFIRKKWLEREDAHSPNQ-----------IMYKACSEMLNQVWYWGEIS 195
            ||:.|.||..|..:.        .|.....:.|:           .:.|..|.:....||||.|:
Mouse   100 PAMQPLPTGAFPEEV--------TEETPVQAENEPKVLDPEGDLLCIAKTFSYLRESGWYWGSIT 156

  Fly   196 RRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLHYRLEYRDNFWHFEE--------LKY 252
            ..::::.|...|.|:||||||......||||.:......:.|:||.|:.:..:.        |.:
Mouse   157 ASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAF 221

  Fly   253 ESIVEMIEDILHRCTNDNF-------------VCFVKVPNEMQPPFPVI------LKYPLSRYSN 298
            ..:|.:::..:..|..|..             :.....|::...|.||.      |..|..|.|:
Mouse   222 PDVVSLVQHYVASCAADTRSDSPDPAPTPALPMSKQDAPSDSVLPIPVATAVHLKLVQPFVRRSS 286

  Fly   299 MPKLQDLCRRVLQRQMSREQLAQLPVPAQMLEYLSVERELVFQ 341
            ...||.|||.|:.|.::  .:..||:|.:|.:||   |:..||
Mouse   287 ARSLQHLCRLVINRLVA--DVDCLPLPRRMADYL---RQYPFQ 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs44A	NP_523659.1	SH2_SOCS_family	188..266	CDD:198178	24/85 (28%)
		SOCS	293..333	CDD:295349	14/39 (36%)
Cish	XP_006511698.1	SH2_CIS	145..232	CDD:198285	24/86 (28%)
		SOCS_CIS1	285..325	CDD:239703	17/45 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740