DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nup50 and AT4G11790

DIOPT Version :9

Sequence 1:	NP_610355.1	Gene:	Nup50 / 35784	FlyBaseID:	FBgn0033264	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_567381.1	Gene:	AT4G11790 / 826785	AraportID:	AT4G11790	Length:	443	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	101/475 - (21%)
Similarity:	185/475 - (38%)	Gaps:	104/475 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 AKESTSTVDGAKPTTSIFGNISAAKKESSEAKTSSSSTSLTSTMETSEY-RESVADLNRSVIKFL 210
            ::.:.|....|||...||    ...:::......||.||.:...:.:|. |:.|..||...:.::
plant    10 SESNDSPFKNAKPVEGIF----FGTQKNVVPMQQSSVTSASLDKQRAELARKHVRALNNQFVSWV 70

  Fly   211 QDQMGKSPYCILTPVFKNYDEHLKDLQDEESARTNSTKSKTAQARSQEPVAKVSRASSPPKAATT 275
            |.|:...|..:......:|..|..::.::.....:..|....:..:..|.::
plant    71 QLQLKNHPDELWEDGMNDYITHASNILEKFKDVVSWLKENKGKGENLSPESR------------- 122

  Fly   276 FTFGKPSAPIGASVSPLAKKPNCTITSGGTTTTTAT----PLVSFGSTASFTAPVPSSSSIFS-- 334
                      ||....:|:..|..:.|.......|:    .:.|...::.|::   |.|..||
plant   123 ----------GAENKLVAEVKNTNVKSFSNNIPFASNNQPGIFSNNQSSDFSS---SQSGFFSSQ 174

  Fly   335 ---LTAKPTGEAKSDDTPKSSIFSFGAKDTTTKKDEPN-FSAPKTNGFS-----------FGLKS 384
               .::.|:|...:..|...|...||    |||..:|: ||..:....|           .|:.|
plant   175 SGAFSSSPSGLISNSQTGSFSSGQFG----TTKSSQPSLFSGSQAGAISNSQPGTFSSSHSGITS 235

  Fly   385 NNDDKPSTSLFAG--FGKA------------PGGAGDGAKGFSFTNSATPFSLGNIHPPAAAAAP 435
            |:    .|..|:.  ||:.            .|........|.|:||.:||:  :..||.:..|.
plant   236 NS----QTGSFSSGQFGQTKSSQPSLLSGSQAGAISSNQPSFQFSNSQSPFT--SAVPPVSIPAK 294

  Fly   436 AE--------EEKEEDTPPKVEFKQVVEDDAIYSKRCKVFIKK----DKDFGDRGVGTLYL---- 484
            .:        :|:.:.:.|.|:..:......::..:||:::|.    ||.:.|:|.|.||:
plant   295 QDHSDDADGGDEQSQPSSPSVKKTEEKGITVVHEVKCKLYVKSSDPADKGWKDKGTGNLYIKCKE 359

  Fly   485 ---KPVKDSEKIQLLVRADTNLGNILVNLILSKGIPCQRMGKNNVLMVCVPTPEDSKAT----SL 542
               |..|:| |..:|||.|  :|.:|:|.:|..|:  :...:.|.|:....:.:||...    :.
plant   360 GVDKGTKES-KPTILVRND--VGKLLLNALLYAGM--KTSPQKNALVAIFHSSDDSNENVTPRTF 419

  Fly   543 LLRVKTGDEADDLLEKIKEH 562
            |:|.|..:..|:|...|:|:
plant   420 LIRTKNAEARDNLATAIQEY 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup50	NP_610355.1	NUP50	4..80	CDD:312461
Nup50	NP_610355.1	RanBD_NUP50	453..563	CDD:269991	34/125 (27%)
AT4G11790	NP_567381.1	RanBD_NUP50	318..440	CDD:269991	34/127 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4720
eggNOG	1	0.900	-	-		E1_KOG2724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I2507
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23138
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050