Protein Alignment Nup50 and npp-16

DIOPT Version :9

• Sequence 1: NP_610355.1
• Gene: Nup50 / 35784
• FlyBaseID: FBgn0033264
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_499551.1
• Gene: npp-16 / 176623
• WormBaseID: WBGene00003802
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 139/586 - (23%)
• Similarity: 219/586 - (37%)
• Gaps: 169/586 - (28%)

  Fly    12 NHENWDLEEEPEERGTFRTATEEELKTRVIKKARRKIAGG-------SSAAEEDGAEEKTAEPKS 69
            ||.::.        ||.::..:...:.:.|.|....:|..       .:::|..|   :|..|:.
 Worm    42 NHYDFS--------GTMKSYMDHVAQLKQIYKVDDDVAADMTVPRRTENSSESSG---ETVAPRK 95

  Fly    70 VFSGFSGFGKPAASPAAGSPFSFLANVTAPATTSSSEPKKSAFSFGFSSSSSSADRPVSTSICGT 134
            :.......|.| .:|...:.|:    .::||.|.:|.||     ||        |..|.|
 Worm    96 IAKAVRKNGTP-KNPLNSTVFA----ASSPAATVASVPK-----FG--------DISVIT----- 137

  Fly   135 ASTSSTAPSPLPAKESTSTVDGAKPTTS----------IFGNISAAKKESSEAKTSSSSTSLTST 189
                ...|:|| ||.:...|..|.|.|:          :.|..|...|...:.:.::||..:.:|
 Worm   138 ----KETPAPL-AKTAEPLVAPAAPATARKRAIRGGGPLGGAESVVFKSGEDGQAATSSVKIPAT 197

  Fly   190 METSEYRESVADLNRSVIKFLQDQMGKSPYCILTPVFKNYDEHLKDLQDEESARTNSTKSKTAQA 254
                            .|||                    .|..||..      |..:.:..|.:
 Worm   198 ----------------TIKF--------------------PEPTKDFW------TKKSDAPAAPS 220

  Fly   255 RSQEPVAKVSRASSPPKAA---TTFTFG-KPSAPIGASVSPLAKKPNCTITSGGTTTTTATPLVS 315
            .|....|.:.:....||..   :.|:|| ||:.|   |..|.|              ..:||.::
 Worm   221 NSGSLFAFLGKDGDKPKETPKFSGFSFGKKPAEP---SEEPKA--------------ADSTPKLT 268

  Fly   316 FGSTASFTAPVPSSSSIFSLTAKPT--GEAKSDDT---PK--------SSIFSFGAKDTTTKKDE 367
            |||......|.|:||...:..:||.  |.:.:|.|   ||        :|:|...:..|||...:
 Worm   269 FGSPKEADLPKPASSLFGASPSKPLVFGGSSADSTTSAPKPFSALSTAASLFGSSSASTTTTATQ 333

  Fly   368 PNFSAPKTNGFSFGLKSNNDDKPSTSLFAGFGKAPGGAGDGAKGFSFTNSATPFSLGNIHPPAAA 432
            |         .|||..|..    .:|||:||      ||...|.....|.|.|...|
 Worm   334 P---------LSFGSSSTG----GSSLFSGF------AGLAQKAMENQNQAKPEGSG-------- 371

  Fly   433 AAPAEEEKEEDTPPKVEFKQVVEDDAIYSKRCKVFIKKDKDFGDRGVGTLYLKPVKDSE-KIQLL 496
                |:::.|..|||||..:..|.||:.|.:..||....|::...|||.|:   :||:: |..:|
 Worm   372 ----EDDEGEYVPPKVETVENQEPDAVLSSKVSVFKFTGKEYTKLGVGMLH---IKDNDGKFSVL 429

  Fly   497 VRADTNLGNILVNLILSKGIPCQRM-GKNNVLMVCVPTPEDSKATSLLLRVKTGDEADDLLEKIK 560
            :||.|..|.:.:|.:.:|.:....: .|.:.:.:..|:.....|| :::|..|.|.|....:||.
 Worm   430 IRAATATGTVWLNSLCNKAMKATVVDAKGDRIRLTCPSSSTEMAT-MMIRFGTADGAKKFTDKIL 493

  Fly   561 E 561
            |
 Worm   494 E 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup50	NP_610355.1	NUP50	4..80	CDD:312461	12/74 (16%)
		RanBD_NUP50	453..563	CDD:269991	32/111 (29%)
npp-16	NP_499551.1	RanBD_NUP50	387..496	CDD:269991	32/112 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159729
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I3754
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005423
OrthoInspector	1	1.000	-	-		oto18587
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23138
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4031
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.020