Protein Alignment Asap and GLO3

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_011048.1
• Gene: GLO3 / 856859
• SGDID: S000000924
• Length: 493
• Species: Saccharomyces cerevisiae
• Alignment Length: 639
• Identity: 122/639 - (19%)
• Similarity: 199/639 - (31%)
• Gaps: 262/639 - (41%)

  Fly   386 AEDEGDQKAWMAVLVNCKEKALTKAFQHANPQMSPSLVELQKTVIRYVQLLPGNDRCCDCGSRND 450
            :.|||:..|        .|:...:.||.....|.                   |..|.|||::|.
Yeast     2 SNDEGETFA--------TEQTTQQVFQKLGSNME-------------------NRVCFDCGNKNP 39

  Fly   451 VTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRG 515
             ||.|:.||:::|||||.|||::|||.:.::|.|||..|..||...:..||....|......|:
Yeast    40 -TWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLDKWTINNLRRFKLGGNHKARDFFLKNNGK- 102

  Fly   516 KLQHESSMEERYDFIRAKY---VAKRYVMRTCSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLT 577
            :|.:.::::     .:.||   |||:|.:..   |..::.|:|
Yeast   103 QLLNTANVD-----AKTKYTSPVAKKYKIHL---DKKVQKDME---------------------- 137

  Fly   578 CCLPSSDAGETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCALH 642
             ..||.
Yeast   138 -LYPSE----------------------------------------------------------- 142

  Fly   643 DRRECMKLLLRSGADYELKNSQNKTALDIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNE 707
                    |:.:|.|      .:.:.||...:...::.:|          ::.|...::|..|:.
Yeast   143 --------LVLNGQD------SSDSPLDTDSDASRSTSKE----------NSVDDFFSNWQKPSS 183

  Fly   708 DGS---------------TDFSDDETVIDERKSRSRPPSFAGGDSPVLRSRSSTCDSIQSSSSPI 757
            :.|               |..|..:|.:.:.:|....   |....|||.|:.....||.|||..
Yeast   184 NSSSKLNVNTGSLAPKNNTTGSTPKTTVTKTRSSILT---ASRKKPVLNSQDKKKHSILSSSRK- 244

  Fly   758 ANCPSR----------------------------QFTLPSGLPSYTHSAGTSPKQHISVGQYLGS 794
               |:|                            :||        ..|:.|..:|:....|::
Yeast   245 ---PTRLTAKKVDKSQAEDLFDQFKKEAQQEKEDEFT--------NSSSSTKIRQNDYDSQFM-- 296

  Fly   795 ATNVGGNGPGNGGSSPSSASSQS------VRAARNSLNM----QSD--------LGGHVTGARKS 841
                 .|..||..:|....::|.      :....||.:.    |.|        ||..:| ...:
Yeast   297 -----NNSKGNNNNSIDDINTQPDEFNDFLNDTSNSFDTTRKEQQDTLTPKFAKLGFGMT-MNDA 355

  Fly   842 TSTANMNSLKKRTAPAP--------PPGTLGSASSSSFYGTLPHPPRHSQNFDASDIRAINHKNQ 898
            ...|......::.|..|        ..||..:.||...:|        ..:||.:..|..:.|.:
Yeast   356 NDLAKQQKESQKIAQGPRYTGRIAERYGTQKAISSDQLFG--------RGSFDEAANREAHDKLK 412

  Fly   899 SLDVAYGTLPHLRSVESSPRGG-----GGYGYGVSQDPGGSGN----GSNNSLM 943
            :.|.|       .|:.||...|     ..:|..::....|:||    .|||..:
Yeast   413 TFDNA-------TSISSSSYFGEDKEVDEFGNPINSSGSGAGNFDGRNSNNGFI 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071	5/23 (22%)
		ArfGap_ASAP	425..541	CDD:350063	40/118 (34%)
		Ank_2	554..662	CDD:403870	6/107 (6%)
		ANK repeat	586..622	CDD:293786	0/35 (0%)
		ANK repeat	624..662	CDD:293786	3/37 (8%)
		Ank_2	636..>693	CDD:403870	6/56 (11%)
		SH3_ASAP	1095..1149	CDD:212755
GLO3	NP_011048.1	COG5347	9..363	CDD:227651	95/519 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810