DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asap and SPS18

DIOPT Version :9

Sequence 1:	NP_001014504.1	Gene:	Asap / 35783	FlyBaseID:	FBgn0050372	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_014195.1	Gene:	SPS18 / 855517	SGDID:	S000005148	Length:	300	Species:	Saccharomyces cerevisiae

Alignment Length:	125	Identity:	34/125 - (27%)
Similarity:	64/125 - (51%)	Gaps:	5/125 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   423 VELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDN 487
            :|.:|.::| .:...||:.|.:|.|.|. .::|.:|||.:|:.|:.:.|.:|.:...::|:|:||
Yeast    10 MENRKRLLR-AKKAAGNNNCFECKSVNP-QFVSCSFGIFICVNCANLLRGMGTNIFCVKSITMDN 72

  Fly   488 LTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFIRAKYVAKRYVMRTCSDD 547
            ....::......||:.....:..   .|.||:...:.|:||.:.||...:|......|:|
Yeast    73 FEEKDVRRVEKSGNNRFGSFLSK---NGILQNGIPLREKYDNLFAKSYKRRLANEVRSND 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	31/115 (27%)
		Ank_2	554..662	CDD:403870
		ANK repeat	586..622	CDD:293786
		ANK repeat	624..662	CDD:293786
		Ank_2	636..>693	CDD:403870
		SH3_ASAP	1095..1149	CDD:212755
SPS18	NP_014195.1	COG5347	6..300	CDD:227651	34/125 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810