DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asap and GTS1

DIOPT Version :9

Sequence 1:	NP_001014504.1	Gene:	Asap / 35783	FlyBaseID:	FBgn0050372	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_011334.1	Gene:	GTS1 / 852694	SGDID:	S000003149	Length:	396	Species:	Saccharomyces cerevisiae

Alignment Length:	136	Identity:	29/136 - (21%)
Similarity:	61/136 - (44%)	Gaps:	25/136 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   419 SPSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDL-GVH----HS 478
            |.||..:.:.:...:......::|.:||:... ||.|:|.|:.:|.:|:.|||.: |..    .|
Yeast     7 SHSLKHVDRELKELINSSENANKCGECGNFYP-TWCSVNLGVFLCGRCASVHRKVFGSRDDDAFS 70

  Fly   479 RIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYD----------FIRAK 533
            .::||::|..|..::....::|.:.         |..:..:..::...:|          :||.|
Yeast    71 NVKSLSMDRWTREDIDELVSLGGNK---------GNARFWNPKNVPFPFDGDDDKAIVEHYIRDK 126

  Fly   534 YVAKRY 539
            |:..::
Yeast   127 YILGKF 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	26/130 (20%)
		Ank_2	554..662	CDD:403870
		ANK repeat	586..622	CDD:293786
		ANK repeat	624..662	CDD:293786
		Ank_2	636..>693	CDD:403870
		SH3_ASAP	1095..1149	CDD:212755
GTS1	NP_011334.1	COG5347	8..310	CDD:227651	28/135 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900