Protein Alignment Asap and AGD2

DIOPT Version :10

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_176283.1
• Gene: AGD2 / 842378
• AraportID: AT1G60860
• Length: 776
• Species: Arabidopsis thaliana
• Alignment Length: 801
• Identity: 180/801 - (22%)
• Similarity: 311/801 - (38%)
• Gaps: 204/801 - (25%)

  Fly    47 FDREGLT--------KLKKAVKAIHNS-GNTHVDNEMFMVRALERLGGKVIEQDEP---DIGAAF 99
            |..||.:        ||.|.||....: |........| ..:||..|.   ..|:|   .||...
plant    18 FSLEGTSDELKDRCQKLYKGVKKFMGALGEASTGVSAF-ADSLEEFGA---GHDDPVSVSIGGPV 78

  Fly   100 L-KFSVVTKELSALMKTLMQNINNIVMFPVDSMLKSELRGVKGDMKRPFDKAAKDYE---AKFIK 160
            : ||....:|||:..:.|...:.::::..:.:.:..:|:..| :.:|.||||...|:   .||:.
plant    79 ISKFINTLRELSSYKEFLRSQVEHVLLERLTNFMTVDLQEAK-ESRRRFDKAVHSYDQAREKFVS 142

  Fly   161 IEKEKKAQAKEAGMVRTEIDAAVVAEEMEKERRLYQLQTCEYLLKYKDIKTKTGIELLQHLIEYY 225
            ::|..:      |.:..|::     |::|..:..::......:.....|:.|...|.|:.:....
plant   143 LKKNTR------GDIVAELE-----EDLENSKSAFEKSRFNLVNSLMTIEAKKKYEFLESISAIM 196

  Fly   226 HALSNYFKDGLQTIEHFGTYIGDL----SEKLHEIKQKQDEDRRSLLDLRTVLRSTPDFERVDNV 286
            .:...|||.|...:.....||..:    .:...:.|.:||...:.:.:.||  :|..|.::....
plant   197 DSHFKYFKLGYDLLSQLEPYIHQVLTYAQQSKEQSKIEQDRFAQRIQEFRT--QSELDSQQASAK 259

  Fly   287 PSSESRSGGAGYSLHQLQ---------GDKHHGVTRQGHLLKKSEGKVRRVWQKRRCRVTSDGFL 342
            .......|...|.....:         .||.  ||:||:|||:| ..:|..|::|...:.:.|.|
plant   260 ADPSDVGGNHVYRAIPRKNVEANSVSTADKE--VTKQGYLLKRS-ASLRADWKRRFFVLDNHGSL 321

  Fly   343 DIFHADESKPP---------------------TR--------------VNLLTCQIKPVPDD--- 369
            ..:....:|..                     ||              ::|.|..||...:|
plant   322 YYYRNTGNKSAKSQHYYSGLGEHSSGVFGRFRTRHNRSASQGSLDCNMIDLRTSLIKLDAEDTDL 386

  Fly   370 KRGFDLISYNRPYHFQAEDEGDQKAWM-----AVLVNCKEKALTKA----FQHANPQMSPSLVEL 425
            :..|.:||..:.|..|||:..|:..|:     |:.:......|.::    ....|....|:...|
plant   387 RLCFRIISPQKTYTLQAENGADRMDWVNKITAAITIRLNSHFLQQSPARYLDKKNTSSGPATENL 451

  Fly   426 ---QK-----------TVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVH 476
               ||           .|:..::.:|||:.|.:|.: .|..|.|||.|:|:||:||||||:||||
plant   452 TLNQKEDYNQRLNVGDDVLTILREIPGNNTCAECNA-PDPDWASLNLGVLMCIECSGVHRNLGVH 515

  Fly   477 HSRIQSLTLD-NLTTANLL-IARAMGNSTLNDIME------------------AKLGRGKLQHES 521
            .|:::||||| .:....:| :.|.:||...|.:.|                  |.:.:...:...
plant   516 ISKVRSLTLDVKVWEPTILDLFRNLGNGYCNSVWEELLHHLDDDSEKGSTDTLASVSKPSSEDWF 580

  Fly   522 SMEERYDFIRAKYVAKRYVMRTCSDDN--------------DLRCDLEQAVVNADMSQLLQVWAE 572
            :::|:|  |..||:.|..|::...:.|              ::| |:.:.:|.||.:.:...:.:
plant   581 TLKEKY--INGKYLEKALVVKDEREANSTASSRIWEAVQSRNIR-DIYRLIVKADANIINTKFDD 642

  Fly   573 GADL--------------------TCCLPSSDAGE--------TALHLAVLREMGSTLHIVDFLI 609
            ..||                    ..|....::.|        :.||:|.  :.|..: :::.|:
plant   643 ITDLDVYHHHHVDAPDEVKKRHDPNACQRIKNSNEARNCLQGCSLLHVAC--QSGDPI-LLELLL 704

  Fly   610 Q-----NMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTAL 669
            |     ||              .|..|: |.||.|.........|:|||.||...:::....:.|
plant   705 QFGADINM--------------RDYHGR-TPLHHCIASGNNAFAKVLLRRGARPSIEDGGGLSVL 754

  Fly   670 DIAKEMGHNSCRELI----EC 686
            :.|.|||..:..||.    ||
plant   755 ERAMEMGAITDEELFLLLAEC 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288	48/217 (22%)
		PH_ASAP	302..410	CDD:270071	34/159 (21%)
		ArfGap_ASAP	425..541	CDD:350063	47/149 (32%)
		ANKYR	<573..709	CDD:440430	33/151 (22%)
		ANK repeat	586..622	CDD:293786	9/48 (19%)
		ANK repeat	624..662	CDD:293786	12/37 (32%)
		Vac17	<706..>788	CDD:435863
		SH3_ASAP	1095..1149	CDD:212755
AGD2	NP_176283.1	BAR_SFC_plant	15..216	CDD:153290	46/213 (22%)
		PH_ACAP	293..425	CDD:270070	29/132 (22%)
		ArfGap	470..591	CDD:350058	40/123 (33%)
		ANKYR	<590..774	CDD:440430	41/202 (20%)
		ANK repeat	676..714	CDD:293786	9/54 (17%)
		ANK repeat	716..747	CDD:293786	11/31 (35%)