Protein Alignment Asap and Smap1

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_003750716.3
• Gene: Smap1 / 684800
• RGDID: 1585595
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 128/627 - (20%)
• Similarity: 204/627 - (32%)
• Gaps: 229/627 - (36%)

  Fly   401 NCKEKALTKAFQHANPQMSPSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQ 465
            :|:|||     |..|.|....|.:|.:.        ..|..|.||.::.. .|.|.|.|:.:||:
  Rat     5 SCREKA-----QKLNEQHQLILSKLLRE--------EDNKYCADCEAKGP-RWASWNIGVFICIR 55

  Fly   466 CSGVHRDLGVHHSRIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFI 530
            |:|:||:||||.||::|:.||..|...:...:.|||:....:.||.|.....:.::.....: ||
  Rat    56 CAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEF-FI 119

  Fly   531 RAKYVAKRYVMRTCSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVL 595
            |.||..|:|.     |.|.:      |:.|                   :.||||
  Rat   120 RDKYEKKKYY-----DKNAI------AITN-------------------ISSSDA---------- 144

  Fly   596 REMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYEL 660
                             |.:.|  .::|:             |.|..|:.:..|       :.|.
  Rat   145 -----------------PLQPL--VSSPS-------------LPAAVDKNKIEK-------EKEK 170

  Fly   661 KNSQNKTALDIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKS 725
            |..:.|              ||      |..:.....:.|:.....||..          .|.|.
  Rat   171 KKEEKK--------------RE------KEPEKPAKALTTEKLQKKEDQQ----------PEPKK 205

  Fly   726 RSRPPSFA-----------GGDSPVLRSRSSTCDSIQ----------SSSSPIANCPSRQFT--L 767
            .:.|.:.|           ..::||....::....:.          |:..|.|..|..|.|  :
  Rat   206 STSPKNVAEPTVDLLGLDGPAEAPVTNGNTTAAPPLSDDLDIFGPMISNPLPAAVMPQAQGTASI 270

  Fly   768 PSGLPSYTHSAGTSPKQHISVGQYLGSATNVGGNGPGNGGSSPSSASSQSVRAARNSLNMQSDLG 832
            |:.....|.::|.           |...|               ..:::|...|:..|:..|.|.
  Rat   271 PAAAALSTITSGD-----------LDLFT---------------EQTTKSEEGAKKQLSKDSILS 309

  Fly   833 GHVTGARKSTSTANMN------SLKKRTA---------PAP-PPGTLGSASSSSFYGTLPHPPRH 881
            .:.|||::||....|.      :.:..||         |.| .||.:|:....: .|.:...|.|
  Rat   310 LYGTGAQQSTPGVFMGPTNIPFTSQAPTAFQGFPSMGVPVPAAPGLMGNMMGQN-TGMMVGMPMH 373

  Fly   882 SQNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRGG---------GGYGYGVSQDPG----- 932
            :....              :...|.:|..::| ..|:||         ..:|...:|.|.
  Rat   374 NGFMG--------------NAQTGVMPLPQNV-VGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQ 423

  Fly   933 ----------GSGNGSNNSLMPAMTTFGHKRSPSGESLNRNI 964
                      .|.|.|.....|..||.|...|.||::|:..:
  Rat   424 MNQQMAAMNLSSANSSAGFGQPPSTTAGWSGSSSGQTLSTQL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071	4/8 (50%)
		ArfGap_ASAP	425..541	CDD:350063	38/115 (33%)
		Ank_2	554..662	CDD:403870	14/107 (13%)
		ANK repeat	586..622	CDD:293786	2/35 (6%)
		ANK repeat	624..662	CDD:293786	5/37 (14%)
		Ank_2	636..>693	CDD:403870	10/56 (18%)
		SH3_ASAP	1095..1149	CDD:212755
Smap1	XP_003750716.3	ArfGap	20..120	CDD:279720	33/109 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900