Protein Alignment Asap and ArfGAP1

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 629
• Identity: 117/629 - (18%)
• Similarity: 186/629 - (29%)
• Gaps: 232/629 - (36%)

  Fly   414 ANPQMSPSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHS 478
            |:|:....|.||:..        ..|.:|.:||:.|. .|:|:.:||.:|::|||.||.||||.|
  Fly     2 ASPRTRRVLQELKPQ--------DENSKCFECGTHNP-QWVSVTYGIWICLECSGKHRSLGVHLS 57

  Fly   479 RIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFIRAKYVAKRYVMRT 543
            .::|:|:|......|...:|.||....:.:|
  Fly    58 FVRSVTMDKWKDIELEKMKAGGNRNAREFLE---------------------------------- 88

  Fly   544 CSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHIVDFL 608
              |..|                    |.|.|.:|....|..|       |:.|:..:|
  Fly    89 --DQED--------------------WNERAPITQRYNSKAA-------ALYRDKIAT------- 117

  Fly   609 IQNMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTALDIAK 673
                                                       |..|..::||.:|.:...:.:.
  Fly   118 -------------------------------------------LAQGKSWDLKEAQGRVGSNNSF 139

  Fly   674 EMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDG----------STDFSDDETVIDERK---S 725
            ..|.:|     ..:.:...||..: ..:....|..|          :.:|.|.:.....|:   :
  Fly   140 SSGGSS-----NSSYQSRPSATGY-GGNGGYQNGGGAEPGGYQQYQTQEFKDQKEEFFSRRQVEN 198

  Fly   726 RSRP---PSFAGGD--------SPVLRSRS-----STCDSIQS-------SSSPIANCPSRQFTL 767
            .|||   |...||.        .|..:::|     ||..::.|       ::|.:|:....:...
  Fly   199 ASRPENLPPSQGGKYAGFGFTREPPPKTQSQELFDSTLSTLASGWSLFSTNASKLASTAKEKAVT 263

  Fly   768 PSGLPSYTHSAGT-SPKQHISVGQYLGSATNVGGNG----PGNGGSSPSSASSQSVRAARNSLNM 827
            ...|.|.....|| .......|.......|::|..|    .|:..|||....:.......::...
  Fly   264 TVNLASTKIKEGTLLDSVQCGVTDVASKVTDMGKRGWNNLAGSNISSPQGGYNDPNFEDSSAYQR 328

  Fly   828 QSDLGGHVTGARKSTSTA----------NMNSLKKRTAPAPPPGTLGSASSSSFYGTLPHPPRHS 882
            .:.:||::.|.....|..          |.||....|            ||||::..|
  Fly   329 SNSVGGNLAGGLGQQSGVSDSDWGGWQDNGNSKSHMT------------SSSSYHNQL------- 374

  Fly   883 QNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRGGGGYGYGVSQDPGGSGNGSNNSLMPAMT 947
                                            ||..|||....|:::|...||..:.|  ..:..
  Fly   375 --------------------------------SSSSGGGTASAGLTRDADWSGFEATN--YQSSE 405

  Fly   948 TFGHKRSPSGESLNRNIHLAGAKLVLPPTGELPTLKHVDKSALT 991
            |.....|..|.:..||:.|......|....|...:|.|.....|
  Fly   406 TSYQNASSGGSTARRNMKLQDTSQKLSEGFESLDVKSVKPKTAT 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	29/115 (25%)
		Ank_2	554..662	CDD:403870	12/107 (11%)
		ANK repeat	586..622	CDD:293786	3/35 (9%)
		ANK repeat	624..662	CDD:293786	3/37 (8%)
		Ank_2	636..>693	CDD:403870	7/56 (13%)
		SH3_ASAP	1095..1149	CDD:212755
ArfGAP1	NP_524040.2	ArfGap	7..114	CDD:279720	41/178 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464128
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740