Protein Alignment Asap and Arfgap2

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_006234592.1
• Gene: Arfgap2 / 362162
• RGDID: 1306177
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 120/610 - (19%)
• Similarity: 192/610 - (31%)
• Gaps: 201/610 - (32%)

  Fly   420 PSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLT 484
            ||..|:| |:.:.::.:|.|..|.|||:::. :|.|:.:|:.:||.||||||.||||.|.|:|..
  Rat     5 PSKSEIQ-TLFKRLRAIPTNKACFDCGAKSP-SWASITYGVFLCIDCSGVHRSLGVHLSFIRSTE 67

  Fly   485 LD-NLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFIRAKYVAKRYVMRTCSDDN 548
            || |.:...|...:..||:........   .|.|.::::         .||
  Rat    68 LDSNWSWLQLRCMQVGGNANATAFFRQ---HGCLANDAN---------TKY-------------- 106

  Fly   549 DLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTL---HIVDFLIQ 610
                          .|:..|::.|                     .:|::|||.   |..|..|.
  Rat   107 --------------NSRAAQMYRE---------------------KIRQLGSTALARHGTDLWID 136

  Fly   611 NM---------------------PPKGLNKATNPAGLLDVT-------------GKNT------- 634
            ||                     .|.....||:|:|.....             |.||
  Rat   137 NMNSAPSHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSESSSLAQPEPGPNTDLLGTSP 201

  Fly   635 -----ALHLCA--LHDRRECMKLLLRSGADYELKNSQNKTALDIAKEMGHNSCRELIECAIKRE- 691
                 :::|.|  |...||     |:|....:.|.:..|..|...|.:|...........|:|:
  Rat   202 QASLESMYLSAKGLSSTRE-----LKSSIIGKKKPAAAKKGLGAKKGLGAQKVSNQSFTEIERQA 261

  Fly   692 ---------------KSAFDHINTDWNLPNEDGSTDFSDDETVID--ERKSRSRPPSFAGGDSPV 739
                           |.|.:.:.....|..::...|...:|..:.  |.|.|.:......|
  Rat   262 QVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMG---- 322

  Fly   740 LRSRSSTCDSIQS------SSSPIANCPSRQ--------FTLPSGLPSYTHSAGTSPKQHISVGQ 790
            |.||||...|:.|      ..:|::...||.        .|..||.|.|..:.       .|:|:
  Rat   323 LVSRSSISHSVLSEMQMIEQETPLSAKSSRSQLDLFDDVGTFASGPPKYKDNP-------FSLGE 380

  Fly   791 YLGSATNVGGN-GPGNGGSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLKKRT 854
            ..||..:.... |...........:..|:|........:.::...::|...|.:.......|
  Rat   381 TFGSRWDSDAAWGMDRVEEKEPEVTISSIRPISERTTSRREVESRISGLESSEARQKFAGAK--- 442

  Fly   855 APAPPPGTLGSASSSSFYGTLPHPPRHSQNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRG 919
                      :.||..|:|                        :.:|..|.....|:.:..|...
  Rat   443 ----------AISSDMFFG------------------------REVDSEYEARSRLQQLSGSSAI 473

  Fly   920 GGGYGYGVSQDPGGSGNGSNNSLMP 944
            .....:|......|.|..|..:::|
  Rat   474 SSSDLFGDVDGAHGGGTVSLGNVLP 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	36/116 (31%)
		Ank_2	554..662	CDD:403870	27/158 (17%)
		ANK repeat	586..622	CDD:293786	11/59 (19%)
		ANK repeat	624..662	CDD:293786	11/64 (17%)
		Ank_2	636..>693	CDD:403870	14/74 (19%)
		SH3_ASAP	1095..1149	CDD:212755
Arfgap2	XP_006234592.1	PLN03114	12..484	CDD:178661	112/586 (19%)
		ArfGap	14..117	CDD:214518	37/164 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900