Protein Alignment Asap and Agfg2

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_006249202.1
• Gene: Agfg2 / 304375
• RGDID: 1306590
• Length: 488
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 123/631 - (19%)
• Similarity: 190/631 - (30%)
• Gaps: 253/631 - (40%)

  Fly   438 GNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLLIARAMGNS 502
            ||..|.:|..|. ||::.:..|..||..|||:.|.|...| |::|:::...|...:|..::.||.
  Rat    43 GNRHCFECAQRG-VTYVDITVGSFVCTTCSGLLRGLNPPH-RVKSISMTTFTEPEVLFLQSRGNE 105

  Fly   503 TLNDIMEAKLG----RGKLQHESSMEERY-DFIRAKYVAKRYVMRTCSDDNDLRCDLEQAVVNAD 562
            ....|.   ||    |..|..:|...::. :|::.||..||:.
  Rat   106 VCRKIW---LGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWY---------------------- 145

  Fly   563 MSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLL 627
                                                             :||:.:..|:...|.:
  Rat   146 -------------------------------------------------VPPEQVKGASYSKGSV 161

  Fly   628 DVT--------GK--NTAL--HLCALHDRRECMKLLLRSGADYELKNSQNKTA-LDIAKEMGHNS 679
            ..|        ||  .|.|  .:.:|.|        ..|.:...:..||.:|| ...::...|:|
  Rat   162 SATPVQGSVPEGKPIRTLLGDPVPSLSD--------AASTSSQSVSQSQARTAQARSSQPPSHSS 218

  Fly   680 CRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKSRSRPPSFA-----GGDSPV 739
            .::               .:||  |..:.|...|:..:..          |:||     ||.:|
  Rat   219 TKK---------------ASTD--LLADIGGDPFAAPQVA----------PAFASFPGFGGQNP- 255

  Fly   740 LRSRSSTCDSIQSSSSPIANCPSRQF-TLPSGLPSYTHSAGTSPKQHISVGQYLGSATNVGGNGP 803
              |.....:....||||    .|..| :||..:.:...:..|.....:..|.|
  Rat   256 --SHGGFANFDAFSSSP----SSSAFGSLPPSVQTPFQAQPTPAANRMLTGSY------------ 302

  Fly   804 GNGGSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLKKRTAPAPPPGTLGSASS 868
             :.|||..||...:..||.:..|..:|:||               .|:.|.|....||
  Rat   303 -SFGSSQMSAFGVAPLAAASQPNSLADVGG---------------LLEPRMAAGGLPG------- 344

  Fly   869 SSFYGTLPHPPRHSQNFDASDIRAINHKNQSLDVAYGTL---------PHLRSVES-SPRG---G 920
             |.:|.....|....        |:.....|..:.:|..         |.|.|... .|.|   |
  Rat   345 -SVFGMPSQVPALQS--------AVPGVGGSTGLPFGAFTNPFTTPAQPQLPSTNPFQPNGIASG 400

  Fly   921 GGYGYGVSQDPGGSGNGSNNSLMPAMTTFGHKRSPSGESLNRNIHLAGAKLVLPPTGELPTLKHV 985
            .|||.| |..||        .|.||                            ||:|...:
  Rat   401 PGYGMG-SVQPG--------LLQPA----------------------------PPSGAFAS---- 424

  Fly   986 DKSALTRPKIPPPGPPSEREISNGQSNESI-----SSMDEGPVAPP 1026
                    ..|.|..|::..:...|:..|.     |.:.:.|::.|
  Rat   425 --------TFPAPVFPTQAGLVEQQNGSSFGDLGTSKLGQRPLSQP 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	33/107 (31%)
		Ank_2	554..662	CDD:403870	12/119 (10%)
		ANK repeat	586..622	CDD:293786	3/35 (9%)
		ANK repeat	624..662	CDD:293786	9/49 (18%)
		Ank_2	636..>693	CDD:403870	10/59 (17%)
		SH3_ASAP	1095..1149	CDD:212755
Agfg2	XP_006249202.1	ArfGap	40..152	CDD:295313	35/184 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900