Protein Alignment Asap and Smap2

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001094139.1
• Gene: Smap2 / 298500
• RGDID: 1308418
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 125/545 - (22%)
• Similarity: 196/545 - (35%)
• Gaps: 150/545 - (27%)

  Fly   427 KTVIRYVQLLPG------NDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTL 485
            |.|.||..:|..      |..|.||.|:.. .|.|.|.|:.:||:|:|:||:||||.||::|:.|
  Rat     7 KDVDRYQAVLANLLLEEDNKFCADCQSKGP-RWASWNIGVFICIRCAGIHRNLGVHISRVKSVNL 70

  Fly   486 DNLTTANLLIARAMGNSTLNDIMEAKLGR--GKLQHESSMEERYDFIRAKYVAKRYVMRTCSDDN 548
            |..|...:...:.|||...|.:.||.|..  .:.|.:.::|   .|||.||..|:|:.|:. |.|
  Rat    71 DQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVE---GFIRDKYEKKKYMDRSL-DIN 131

  Fly   549 DLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHIVDFLIQNMP 613
            .||.:.:..            |..|        |..|.|..:...|..::.......|   ..:|
  Rat   132 VLRKEKDDK------------WKRG--------SEPAPEKKMEPVVFEKVKMPQKKED---AQLP 173

  Fly   614 PKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTALD-----IAK 673
            .|...|:..|  ::|:.|.:..: .|:                   :.||:...||:     :|.
  Rat   174 RKSSPKSAAP--VMDLLGLDAPV-ACS-------------------IANSKTSNALEKDLDLLAS 216

  Fly   674 EMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKSRSRPP--SFAGGD 736
            ....:|.......::....|| ..:..:.||..|.||   ..:||   .:|..|:..  |..|..
  Rat   217 VPSPSSVSRKAVGSMPTAGSA-GSVPENLNLFPEPGS---KSEET---GKKQLSKDSILSLYGSQ 274

  Fly   737 SPVLRSRSSTCDSIQSSSSPIANCPSRQFTLPSGLPSYTHSAGTSPKQHISVGQYL----GSATN 797
            :|            |..:..:...|: |...|:..||:   .|.:|...| :|..:    |...:
  Rat   275 TP------------QMPAQAMFMAPA-QMAYPTAYPSF---PGVTPPNSI-MGSMMPPPVGMVAH 322

  Fly   798 VGGNGPGNGGSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLKKRTAPAPPPGT 862
            .|.:|.....:.|:....          .||:.:.|..:|...:.....|.|:
  Rat   323 PGASGMVTPMAMPAGYMG----------GMQASMAGVPSGMMTTQQAGYMASM------------ 365

  Fly   863 LGSASSSSFYGTLPHPPRHSQNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRGGGGYG--- 924
              :|...:.||..|                    .|.|..      :|..:.....|...||
  Rat   366 --AAMPQTVYGVQP--------------------AQQLQW------NLTQMTQQMAGMNFYGANG 402

  Fly   925 ---YGVSQDPGGSGNGSNNSLMPAM 946
               ||.|.. ||:|..:|.:|.|.|
  Rat   403 MMSYGQSMG-GGNGQAANQTLSPQM 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	46/121 (38%)
		Ank_2	554..662	CDD:403870	14/107 (13%)
		ANK repeat	586..622	CDD:293786	6/35 (17%)
		ANK repeat	624..662	CDD:293786	3/37 (8%)
		Ank_2	636..>693	CDD:403870	7/61 (11%)
		SH3_ASAP	1095..1149	CDD:212755
Smap2	NP_001094139.1	ArfGap_SMAP2	16..122	CDD:350083	40/109 (37%)
		PBP1	<102..419	CDD:227507	84/440 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900