Sequence 1: | NP_001014504.1 | Gene: | Asap / 35783 | FlyBaseID: | FBgn0050372 | Length: | 1155 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_722483.2 | Gene: | Acap1 / 216859 | MGIID: | 2388270 | Length: | 740 | Species: | Mus musculus |
Alignment Length: | 811 | Identity: | 193/811 - (23%) |
---|---|---|---|
Similarity: | 313/811 - (38%) | Gaps: | 207/811 - (25%) |
- Green bases have known domain annotations that are detailed below.
Fly 38 IGVLEERLEFDREGLTKLKKAVKAIHNSGNTHV-DNEMFMVRA--LERLGGKVIEQDEPDIGAAF 99
Fly 100 LKFSVVTKE--------LSALMKTLMQNINNIVMFPVDSMLKSELRGVKGDMKRPFDKAAKDYEA 156
Fly 157 KF---IKIEKEKKAQAKEAGMVRTEIDAAVVAEEMEKERRLYQLQTCEYLLKYKDIKTKTGIELL 218
Fly 219 QHLIEYYHALSNYFKDGLQTIEHFGTYIGDLSEKLHEI-----KQKQD-EDRRSLLDLRTVLRST 277
Fly 278 PDFERVDNVPSSESRSGGAGYSLHQLQGDKHHGVTRQGHLLKKSEGKVRRVWQKRRCRVTSDGFL 342
Fly 343 DIFHADESKPPTRV---NLLTCQIKPVPDDKRG--FDLISYNRPYHFQAEDEGDQKAWMAVLVNC 402
Fly 403 KEKALTKAFQHANPQMSP-------------SLVELQ-------------KTVIRYVQLLPGNDR 441
Fly 442 CCDCGSRNDV-TWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLLIARAMGNSTLN 505
Fly 506 DIMEAK---LGRGKLQHESSMEERYDFIRAKYVAKRYVMR------------------------- 542
Fly 543 ------------TCSDDNDLRCDLEQAVVNADMSQ----------LLQVWAEGADLTCCLPSSDA 585
Fly 586 GETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCAL-HDRRECMK 649
Fly 650 LLLRSGADYELKNSQNKTALDIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFS 714
Fly 715 DDETVIDERKSRSRPPSFAGGDSPVLRSRSS 745 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Asap | NP_001014504.1 | BAR_ASAPs | 35..249 | CDD:153288 | 52/224 (23%) |
PH_ASAP | 302..410 | CDD:270071 | 24/112 (21%) | ||
ArfGap_ASAP | 425..541 | CDD:350063 | 48/132 (36%) | ||
Ank_2 | 554..662 | CDD:403870 | 27/118 (23%) | ||
ANK repeat | 586..622 | CDD:293786 | 8/35 (23%) | ||
ANK repeat | 624..662 | CDD:293786 | 12/38 (32%) | ||
Ank_2 | 636..>693 | CDD:403870 | 17/57 (30%) | ||
SH3_ASAP | 1095..1149 | CDD:212755 | |||
Acap1 | NP_722483.2 | Required for formation of endosomal tubules when overexpressed with PIP5K1C. /evidence=ECO:0000250|UniProtKB:Q15027 | 1..382 | 94/416 (23%) | |
BAR_ACAP1 | 18..217 | CDD:153323 | 51/221 (23%) | ||
PH | 266..360 | CDD:278594 | 22/101 (22%) | ||
PH_ACAP | 268..364 | CDD:270070 | 23/103 (22%) | ||
Required for interaction with GULP1. /evidence=ECO:0000250|UniProtKB:Q15027 | 405..740 | 97/371 (26%) | |||
ArfGap | 406..519 | CDD:279720 | 47/114 (41%) | ||
Prevents interaction with ITGB1 when S-554 is not phosphorylated. /evidence=ECO:0000250 | 525..566 | 2/45 (4%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..562 | 0/36 (0%) | |||
Ank_2 | 575..670 | CDD:289560 | 26/109 (24%) | ||
ANK repeat | 575..602 | CDD:293786 | 5/30 (17%) | ||
ANK | <592..692 | CDD:238125 | 29/114 (25%) | ||
ANK repeat | 606..637 | CDD:293786 | 9/39 (23%) | ||
ANK repeat | 639..670 | CDD:293786 | 10/32 (31%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D751525at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.820 |