Protein Alignment Asap and F07F6.4

DIOPT Version :9

• Sequence 1: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_495029.2
• Gene: F07F6.4 / 173927
• WormBaseID: WBGene00017217
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 131/564 - (23%)
• Similarity: 198/564 - (35%)
• Gaps: 152/564 - (26%)

  Fly   420 PSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLT 484
            ||.|:|| |.:|.::.||.|..|.|||:||. ||.::.:|:.:||.||.|||:||||.:.::|..
 Worm     7 PSKVDLQ-TAMRKMRALPPNKLCFDCGARNP-TWCTVTYGVFLCIDCSAVHRNLGVHLTFVRSTN 69

  Fly   485 LD-NLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFIRAKYVAKRYVMRTCSDDN 548
            || |.|...|...:..||...|...:|        |..:..|         ..::|..|......
 Worm    70 LDTNWTWLQLRAMQLGGNGNANQFFKA--------HGCNTTE---------AQQKYKSRAAQMYR 117

  Fly   549 DLRCDLEQAVVNADMSQLL--------QVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHIV 605
            |....|.|.......:||:        :..||..|..    :.|.|.|:   |....:.|..:|.
 Worm   118 DKLSTLCQEAQRKFGTQLIIDTVTHAEEKPAEEEDFF----AQDFGHTS---ASATSLSSDAYIA 175

  Fly   606 DFLIQN---------------MP---------PKGLNKAT-----NPAGLLDV------------ 629
            |...::               :|         .|.:.|||     |..|...|
 Worm   176 DHKSEDSTHGPSVDHLDSSVAVPTSAPVSVILKKPIKKATLGAKKNALGAQKVRINFDEIEQRAA 240

  Fly   630 -TGKNTALHLCA--------------LHDRRECMKLLLR---SGADYELKNSQNKTALDIAKE-- 674
             ..:.||..:.|              ..|.....||..:   ...|.:.|..:.|.|.|..|.
 Worm   241 EKERQTAAEVAANKLAYQTELDGKKKSDDAAALQKLSAKFAMQDIDAQRKQMEAKVAKDPTKAAS 305

  Fly   675 --------MGHNSCRELIECAIKREKSAFDHINT-----------DWNL----------PNEDGS 710
                    :|.:.....:...|:..|.  |.:.|           ||.:          .|||..
 Worm   306 VDRLGMGGVGRSRAAHSVAGGIRSIKQ--DDVLTFKKPSQPKEDDDWEVIDDKYGKKSTNNEDDF 368

  Fly   711 TDFSDDETVIDERKSRSRPPSFAGGDS-PVLRSRSSTCDSIQSSSSPIANCPSRQFTLPSGLPSY 774
              ||.|.|....:|:......|...:: ||.:||.:.    .||||..:..|:.:.|
 Worm   369 --FSKDYTSSSSKKTTKEDDFFDSFETQPVQKSRYTA----SSSSSSTSRAPTTRLT-------- 419

  Fly   775 THSAGTSPKQHISVGQYLGSATNVGGN---GPGNGGSSPSSASSQSVRAARNSLNMQSDLGGHVT 836
               ||.||...:.:.:..|:|..:..:   |.........||.::.  ..:.|...: ||.|:.:
 Worm   420 ---AGASPISDVDLQKKFGNAKAISSDMYFGTPEMDCETRSALTKC--EGQTSFGSE-DLWGNGS 478

  Fly   837 GARKSTSTANMNSLKKR-TAPAPPPGTLGSASSSSFYGTLPHPP 879
            ..|:|:...:|:.||.. .|.|.......|..||||...:...|
 Worm   479 QQRQSSQVPDMSDLKDSFRAGASKVAEKWSTLSSSFSTYMSRAP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	40/116 (34%)
		Ank_2	554..662	CDD:403870	29/174 (17%)
		ANK repeat	586..622	CDD:293786	11/64 (17%)
		ANK repeat	624..662	CDD:293786	9/67 (13%)
		Ank_2	636..>693	CDD:403870	12/83 (14%)
		SH3_ASAP	1095..1149	CDD:212755
F07F6.4	NP_495029.2	ArfGap	16..129	CDD:214518	41/130 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810