DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cul4 and AT1G59790

DIOPT Version :9

Sequence 1:	NP_001163084.1	Gene:	Cul4 / 35780	FlyBaseID:	FBgn0033260	Length:	821	Species:	Drosophila melanogaster
Sequence 2:	NP_176188.1	Gene:	AT1G59790 / 842272	AraportID:	AT1G59790	Length:	374	Species:	Arabidopsis thaliana

Alignment Length:	372	Identity:	97/372 - (26%)
Similarity:	166/372 - (44%)	Gaps:	65/372 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 SKDTYVKLEEAVIAIQLS------------KPIKYSLE--ELYQAVVNMCSHKMD--AQLYAKLK 166
            |:...:|.||....||..            :|..|..|  :||..:.:||..:.|  .|||.|.:
plant     7 SRPRQIKFEEGWSNIQKGITKLIRILEGEPEPTFYFSECFKLYTIIYDMCVQRSDYSQQLYEKYR 71

  Fly   167 ELTEQHVKRNI--KLKELTGGSMDKLILLEKINHW--------WLSFCQQMIMIRSIFLYMDRTY 221
            ::.|.:..:.:  .|:|    ..|:.:|.|.:..|        |||         ..|:|:||..
plant    72 KVIEDYTIQTVLPSLRE----KHDEDMLRELVKRWNNHKIMVKWLS---------KFFVYIDRHL 123

  Fly   222 VLQNS-TVHSIWDMGLDLF-RIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCD 284
            |.::. .:.|:.::||..| .:.:.:.....|..|   :.||.|||:|..:||.|:|:::.:..:
plant   124 VRRSKIPIPSLDEVGLTCFLDLVYCEMQSTAKEVV---IALIHKEREGEQIDRALVKNVLDIYVE 185

  Fly   285 -----LQIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDSSTK 344
                 |:.|...||...|..|...|..::.|..:|...|:|:..|.:.|..|.||:.|||.|.|:
plant   186 NGMGTLEKYEEDFESFMLQDTASYYSRKASRWTEEDSCPDYMIKVEECLKMERERVTHYLHSITE 250

  Fly   345 HPLIYNVEKELLA---------EHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCGN 400
            ..|:..::.|||.         ||      .|..:||.|::.:||:.:|.|...:......:...
plant   251 PKLVEKIQNELLVMVTKNRLENEH------SGFSALLRDDKKNDLSRIYRLYLPIPKRLGRVADL 309

  Fly   401 FNGFIKKKGRTIVIDPEKDKSMVQDLLDFKDKMDVIVRTCFEHNEKF 447
            |...|.::|..::...: ||:..|.|::..:|..|.|..||:::..|
plant   310 FKKHITEEGNALIKQAD-DKTTNQLLIELHNKFIVYVIECFQNHTLF 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul4	NP_001163084.1	Cullin	124..721	CDD:279260	96/366 (26%)
		CULLIN	503..644	CDD:214545
		Cullin_Nedd8	750..815	CDD:214883
AT1G59790	NP_176188.1	Cullin	47..>357	CDD:279260	88/332 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	1	1.000	-	-		FOG0000491
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820