Protein Alignment Tmem63 and AT1G10090

DIOPT Version :9

• Sequence 1: NP_610351.1
• Gene: Tmem63 / 35779
• FlyBaseID: FBgn0033259
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_172480.2
• Gene: AT1G10090 / 837544
• AraportID: AT1G10090
• Length: 762
• Species: Arabidopsis thaliana
• Alignment Length: 675
• Identity: 154/675 - (22%)
• Similarity: 276/675 - (40%)
• Gaps: 132/675 - (19%)

  Fly    35 LNTIFWVLLILLFTVLRHQAGD----FGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVS 95
            :|....|:|:.|:::||.|..:    ||||.   |:|..||....:|.|.|    |.||
plant    12 INIAICVVLVSLYSILRKQPANYCVYFGRLL---SDGRVKRHDPRWYERFA----PSPS------ 63

  Fly    96 PRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALV 160
                                       |:....:..:|.:|...|.|||.::......:.:.::|
plant    64 ---------------------------WLVKAWETTEEEMLAAAGLDAVVFIRMVICSIRIFSIV 101

  Fly   161 TIVSLVIILPVNFLNGPKENPYDVN--AFGRTTMANLSPDSPWLWVHTIITILYIPLVVLIMRRA 223
            .:|.|..:||||:. |.|....:|:  :.|..|:.||:|.|.||||| .:::..|......:...
plant   102 AVVCLAFVLPVNYY-GQKMEHKEVHLESLGVFTIENLNPRSRWLWVH-CLSLYIISSAACALLYF 164

  Fly   224 SGRNAFKKAATRTIMISNISSSDRNKTV-VRNYMQELFPDVTI-ENVSIAYN-------ISRLYV 279
            ..:|..||   |...||..:|...:.|| :|...|.  ||.:. |.||..:.       :|.|.|
plant   165 EYKNIAKK---RLAHISGSASKPSHFTVLIRAIPQS--PDQSYSETVSKYFTNYYAPSYVSHLMV 224

  Fly   280 -RNAEFER-VHEARLYCE--HHRNRDTLMVKPEMCSC-----KKENAYEYYQREERKLSG-DVAR 334
             |:....| ::|....|:  .|.:.| |...|.:.||     ...|:::....|...:.| ::..
plant   225 YRDGFIHRLMNETERMCQAIKHVSPD-LSCNPSLKSCVLCGPAATNSFQIISNETDSVKGLELGE 288

  Fly   335 LRASTMNEPLDIAFI---------TVSTVQEAQNIVTHFTPGTYRQWHLVFAPSPDDLFWENLNV 390
            |..:|..|...:||:         .||.|.:..|.:.         |....||.|.|:.|.||.:
plant   289 LTLTTTEEERPVAFVFFKSRYDALVVSEVLQTPNPML---------WVADLAPEPHDVHWRNLRI 344

  Fly   391 NKSHWYLKFFC--VNAVLFLVLF-----FLSTPAMVVSLLNSRPWVKETEGK--ISPLVADFLPT 446
            .....:::...  |.|:.|:.:|     |:.....:.:|..:.|::|:...:  :..::..:||:
plant   345 PYRQLWMRRIATLVGAIAFMFVFLFPVTFVQGLTQLPTLSKNFPFLKDLLNRRFMEQVITGYLPS 409

  Fly   447 LMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFL 511
            ::|......:|.::..........:||::..|   .|...|...|..:..:.:.|...:.::..|
plant   410 VILVLFFYTVPPLMMYFSTLEGCVSRSQRKKS---ACLKILYFTIWNVFFVNILSGSVIRQFTVL 471

  Fly   512 N---QTDRWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLK---AKSKAETPYI 570
            |   .........:|.:..|::.|..|:.:.|.|.|::   :.:..||:|:.   .|:|.|:
plant   472 NSVRDVPAQLAKLVPAQAGFFMTYCFTSGWAGLACEIM---QPVGLIWNLIAKVIVKNKEES--- 530

  Fly   571 RKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPSNMISR 635
              ...:.||:.|......|...:....||..|||:||.:||....:.:.::.:...|     |::
plant   531 --YETLRFPYHTEIPRLLLFGLLGFTNSVIAPLILPFLLIYFFFAYLIYKNQIINVY-----ITK 588

  Fly   636 --KGGK----IHSTAVTMTKFSVVI 654
              .||:    .|:|.:    ||:::
plant   589 YESGGQYWPVFHNTTI----FSLIL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem63	NP_610351.1	RSN1_TM	32..220	CDD:290675	50/190 (26%)
		PHM7_cyt	270..328	CDD:291375	15/73 (21%)
		RSN1_7TM	347..663	CDD:280815	69/338 (20%)
AT1G10090	NP_172480.2	COG5594	4..652	CDD:227881	154/675 (23%)
		RSN1_7TM	352..616	CDD:397021	55/278 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3494
eggNOG	1	0.900	-	-		E1_COG5594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54295
OrthoDB	1	1.010	-	-		D395194at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2398
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X290
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.830