Protein Alignment Tmem63 and AT3G21620

DIOPT Version :9

• Sequence 1: NP_610351.1
• Gene: Tmem63 / 35779
• FlyBaseID: FBgn0033259
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_188799.1
• Gene: AT3G21620 / 821716
• AraportID: AT3G21620
• Length: 756
• Species: Arabidopsis thaliana
• Alignment Length: 699
• Identity: 136/699 - (19%)
• Similarity: 285/699 - (40%)
• Gaps: 136/699 - (19%)

  Fly   123 WIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDV--N 185
            |:...|::.:..::.|.|.|:|.||......:.:...:..::..:::|||:.|...:...::  :
plant    75 WMPQALRMPEPELIDHAGLDSVVYLRIYLLGLKIFFPIACIAFTVMVPVNWTNSTLDQLKNLTFS 139

  Fly   186 AFGRTTMANLSPDSPWLWVHTIITILYIPLVVLIMRR-----ASGRNAFKKAATR-----TIMIS 240
            ...:.:::|:...|...|||..:..:.......:::|     ||.|..|..:..|     |:::.
plant   140 DIDKLSISNIPTGSSRFWVHLCMAYVITFWTCFVLQREYKHIASMRLQFLASEHRRPDQFTVLVR 204

  Fly   241 NISSSDRNKTV---VRNYMQELFPD--VTIENVSIAYNISRLYVRNAEFERVHEARLYCEHHRNR 300
            || ..|.:::|   |.::.:...||  :|.:.|..|..:|.|..:..:.:.      :.::::|:
plant   205 NI-PPDPDESVSELVEHFFKVNHPDYYLTYQAVYNANKLSELVQKRMKLQN------WLDYYQNK 262

  Fly   301 DTL------MVKPEMCSC--KKENAYEYYQRE----ERKLSGDVARLRASTMNEPLDIAFIT--- 350
            .:.      ::|.....|  ::.:|.::|..:    .||:|.:...:.:|| ...:..||::
plant   263 HSRNPSKRPLIKIGFLGCWGEEVDAIDHYIEKIEGLTRKISEEKETVMSST-KSLVPAAFVSFKK 326

  Fly   351 ------VSTVQEAQNIVTHFTPGTYRQWHLVFAPSPDDLFWENLNVNKSHWYLKFFCVNAVLFLV 409
                  .|..|:::|..         :|...:||.|.|::|:||.:......::...:....|.:
plant   327 RWGAVVCSQTQQSRNPT---------EWLTEWAPEPRDIYWDNLALPYVQLTIRRLVIAVAFFFL 382

  Fly   410 LFFLSTPAMVVSLLNSRPWVKETEGKISPL---------VADFLPTLMLWTLSALMPVIVAISDK 465
            .||...|...|..|.:...:::....:.||         :..|||.:.|.....::|.|:.:..|
plant   383 TFFFMIPIAFVQTLANIEGIEKAVPFLKPLIEVKTVKSFIQGFLPGIALKIFLIVLPSILMLMSK 447

  Fly   466 WMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLNQT----DRWQCIFLPDRG 526
            :....::|.......::.:.:..:.:.:...:..|:.|.|  ..||||:    .:...:.:|.:.
plant   448 FEGFISKSSLERRCASRYYMFQFINVFLCSIIAGTALQQL--DSFLNQSATEIPKTIGVSIPMKA 510

  Fly   527 SFYVNYIITAAFIGTALELLRFPELIVY---IWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTT 588
            :|::.||:...:.|.|.|:||...||:|   .:.|:|.:...|.......|    .|.|......
plant   511 TFFITYIMVDGWAGVAGEILRLKPLIIYHLKNFFLVKTEKDREEAMDPGTI----GFNTGEPQIQ 571

  Fly   589 LVFTIAIVYSVACPLIMPFAMIYICLKHFVDRH---NLY-------FAYGPS------------- 630
            |.|.:.:||:...|:::||.:::..|.:.|.||   |:|       .|:.|.
plant   572 LYFILGLVYAAVSPILLPFILVFFALAYVVYRHQIINVYNQEYESAAAFWPDVHRRVVIALIVSQ 636

  Fly   631 ----NMISRKGGKIHSTAVTMTKFSVVILVLVMAMICFFRGDNGMARFLLLIISLAI-------- 683
                .::|.|      .|...|....::.||.:....|.:|     |:..:.::..:
plant   637 LLLMGLLSTK------KAARSTPLLFILPVLTIGFHKFCQG-----RYQPIFVTYPLQDAMVKDT 690

  Fly   684 -------TLTLFTFMS-----PIKRCAATRRPSIVEIAGPAPIYVPDVL 720
                   .|.|.||:.     |:.:.|......:| :..|||...||::
plant   691 LERMREPNLNLKTFLQNAYAHPVFKAADNLANEMV-VEEPAPDKTPDLV 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem63	NP_610351.1	RSN1_TM	32..220	CDD:290675	17/98 (17%)
		PHM7_cyt	270..328	CDD:291375	9/69 (13%)
		RSN1_7TM	347..663	CDD:280815	75/367 (20%)
AT3G21620	NP_188799.1	RSN1_TM	6..177	CDD:290675	17/101 (17%)
		PHM7_cyt	236..299	CDD:291375	9/68 (13%)
		RSN1_7TM	320..643	CDD:280815	69/337 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3494
eggNOG	1	0.900	-	-		E1_COG5594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54295
OrthoDB	1	1.010	-	-		D395194at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2398
orthoMCL	1	0.900	-	-		OOG6_100323
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X290
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730