DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tmem63 and tmem63bb

DIOPT Version :9

Sequence 1:	NP_610351.1	Gene:	Tmem63 / 35779	FlyBaseID:	FBgn0033259	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001313336.1	Gene:	tmem63bb / 569678	ZFINID:	ZDB-GENE-030131-7663	Length:	179	Species:	Danio rerio

Alignment Length:	174	Identity:	48/174 - (27%)
Similarity:	76/174 - (43%)	Gaps:	34/174 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   610 IYICLKHFVDRHNLYFAYGPSNMISRKGGKIHSTAVTMTKFSVVILVLVMAMICFFR-------G 667
            :|:.|||.|||:|:|:||.||.:    ..||||.||...   |...:|.:..:.||.       .
Zfish     1 MYMLLKHLVDRYNMYYAYLPSKL----DKKIHSGAVNQV---VAAPILCLFWLLFFSTVRIGFLT 58

  Fly   668 DNGMARFLLLIISLAITLT-----LFTFMSPIKRCAATRRPSI--VEIAGPA---------PIYV 716
            ...|..|::|||::.:.|:     .|.::|.......|:...:  ||...||         .:|:
Zfish    59 PTSMFTFVVLIITIVVCLSHVCFGHFKYLSAHNYKIDTKDTEVDGVENGRPARSSPSNKSQQMYI 123

  Fly   717 PDVLKD-NGIRTSSVRPSAAAFGGYGSDSVSEYDSSQYSVNSVE 759
            ..||:| |...|.:   .:....|.||....|..::..|:|..:
Zfish   124 AQVLQDPNSDETGA---GSGEDDGQGSSQDEEMINAGNSLNEAD 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tmem63	NP_610351.1	RSN1_TM	32..220	CDD:290675
		PHM7_cyt	270..328	CDD:291375
		RSN1_7TM	347..663	CDD:280815	21/52 (40%)
tmem63bb	NP_001313336.1	RSN1_7TM	<1..57	CDD:280815	23/62 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D395194at2759
OrthoFinder	1	1.000	-	-		FOG0001439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920