Protein Alignment sand and KCNK17

DIOPT Version :9

• Sequence 1: NP_610349.1
• Gene: sand / 35777
• FlyBaseID: FBgn0033257
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_113648.2
• Gene: KCNK17 / 89822
• HGNCID: 14465
• Length: 332
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 78/349 - (22%)
• Similarity: 136/349 - (38%)
• Gaps: 107/349 - (30%)

  Fly    32 SNVGIILLVTFYIIGGAFIFQSIEIFEYERLKSEKPHRFIARNFSGECLSRIWELTAENISFFDH 96
            |.|.::|....|:..|..:|.::|    .|...:.     :|:|..:    .||| .:|.:..|.
Human    21 STVLLLLAYLAYLALGTGVFWTLE----GRAAQDS-----SRSFQRD----KWEL-LQNFTCLDR 71

  Fly    97 HAYRRRVNDVLLDYQRAIVKKQLKGPDVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTIL 161
            .|....:.||:..|:.. .........:.:|...|:|.:|::.||||||||::|::...:|..|.
Human    72 PALDSLIRDVVQAYKNG-ASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIF 135

  Fly   162 YAIIGMPLFLLYLSNIGDVLAKSFK-WIYSKVCLCRICPGVAKRRIIRERRKMRQLARALQMHDM 225
            :|::|:||.|:.|:.:|.::.:... |
Human   136 FALVGIPLNLVVLNRLGHLMQQGVNHW-------------------------------------- 162

  Fly   226 ENARGSSSYTSTSSTTSSNSSSSEYTRSSRQSSSLVDIQYTESDSDIEREIRGSTDEITVPVTVC 290
                                       :||...       |..|.|..|.:.||        ...
Human   163 ---------------------------ASRLGG-------TWQDPDKARWLAGS--------GAL 185

  Fly   291 VFVMVGYILWGALLFGRWEDWNYLDGSYFCLISLSSIGFGDLV----PGDRVITADRDKVEVSFI 351
            :..::.::|...|||...|.|:|.:|.||..|:||::||||.|    |..|.....::.|
Human   186 LSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMV----- 245

  Fly   352 LCAIYLLLGMAVIAMCFNLMQEQV 375
              ::::|.|||.:|:...|:..|:
Human   246 --SLWILFGMAWLALIIKLILSQL 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	22/59 (37%)
		Ion_trans_2	292..377	CDD:285168	28/88 (32%)
KCNK17	NP_113648.2	Ion_trans_2	96..157	CDD:285168	22/60 (37%)
		Ion_trans_2	<203..268	CDD:285168	24/72 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..312

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155176
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.840