DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sand and TOK1

DIOPT Version :9

Sequence 1:	NP_610349.1	Gene:	sand / 35777	FlyBaseID:	FBgn0033257	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_012442.1	Gene:	TOK1 / 853352	SGDID:	S000003629	Length:	691	Species:	Saccharomyces cerevisiae

Alignment Length:	206	Identity:	49/206 - (23%)
Similarity:	84/206 - (40%)	Gaps:	53/206 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 GAFLYSLTV-ITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCL 194
            |..||..|| :.|:|.|:|.|.|...|::.:::::.|:.|..|.:.....::.||...|:.
Yeast   275 GNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIFF---- 335

  Fly   195 CRICPGVAKRRIIRERRKMRQLARALQMHDMENARGSS-SYTSTSSTTSSNSSSSEYTRSSRQSS 258
                                       .|.:|..|..| .:...||...|...:.:..:..||::
Yeast   336 ---------------------------FHRVEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTA 373

  Fly   259 SLVDIQYTESDSDIEREIRGSTDEITVPVTVCVFVMVGYILWGALLFGRWEDWNYLDGSYFCLIS 323
            |.....::.|                  ||:.:|  :.:.|.|||:|...|:|:|.:..|||.:.
Yeast   374 SRKQHWFSLS------------------VTIAIF--MAFWLLGALVFKFAENWSYFNCIYFCFLC 418

  Fly   324 LSSIGFGDLVP 334
            |.:||:||..|
Yeast   419 LLTIGYGDYAP 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	15/52 (29%)
sand	NP_610349.1	Ion_trans_2	292..377	CDD:285168	18/43 (42%)
TOK1	NP_012442.1	Ion_trans_2	253..328	CDD:400301	15/52 (29%)
TOK1	NP_012442.1	Ion_trans_2	388..462	CDD:400301	18/44 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345205
Domainoid	1	1.000	56	1.000	Domainoid score	I2685
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840