Protein Alignment sand and KCNK16

DIOPT Version :9

• Sequence 1: NP_610349.1
• Gene: sand / 35777
• FlyBaseID: FBgn0033257
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001128577.1
• Gene: KCNK16 / 83795
• HGNCID: 14464
• Length: 322
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 66/313 - (21%)
• Similarity: 119/313 - (38%)
• Gaps: 121/313 - (38%)

  Fly    36 IILLVTFYIIGGAFIFQSIE---------IFEYERLKSEKPHRFIARNFSGECLSRIWELTAENI 91
            ::|....|::.||.|||.:|         .|:.|:|      ||:                 ||.
Human    17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKL------RFL-----------------ENY 58

  Fly    92 SFFDHHAYRRRVNDVLLDYQRAIVKKQLKGPDVEQWSFSGAFLYSLTVITTIGYGNITPHSECGK 156
            :..|..|..:.|..::..:.:.:..|. ...:...|.|..:|.::.||:|||||||:.|.:|.|:
Human    59 TCLDQWAMEQFVQVIMEAWVKGVNPKG-NSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQ 122

  Fly   157 LVTILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCLCRICPGVAKRRIIRERRKMRQLARALQ 221
            :..:.||::|:||.:::|:::|                                       ..|:
Human   123 VFCVFYALLGIPLNVIFLNHLG---------------------------------------TGLR 148

  Fly   222 MHDMENARGSSSYTSTSSTTSSNSSSSEYTRSSRQSSSLVDIQYTESDSDIER-EIRGSTDEITV 285
            .|                                             .:.||| |.|....::..
Human   149 AH---------------------------------------------LAAIERWEDRPRRSQVLQ 168

  Fly   286 PVTVCVFVMVG---YILWGALLFGRWEDWNYLDGSYFCLISLSSIGFGDLVPG 335
            .:.:.:|:.:|   .:::..::|...|.|::.:|.||..|:||:|||||.|.|
Human   169 VLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	22/59 (37%)
		Ion_trans_2	292..377	CDD:285168	18/47 (38%)
KCNK16	NP_001128577.1	Ion_trans_2	<92..148	CDD:311712	22/94 (23%)
		Ion_trans_2	180..>224	CDD:311712	16/42 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9913
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.910