Protein Alignment sand and kcnk5a

DIOPT Version :10

• Sequence 1: NP_610349.1
• Gene: sand / 35777
• FlyBaseID: FBgn0033257
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001032478.2
• Gene: kcnk5a / 570159
• ZFINID: ZDB-GENE-051113-112
• Length: 513
• Species: Danio rerio
• Alignment Length: 378
• Identity: 87/378 - (23%)
• Similarity: 128/378 - (33%)
• Gaps: 164/378 - (43%)

  Fly    40 VTFYIIGGAFIFQSIEIFEYERLKSEKPHRFIARNFSGECLSRIWELTAENISFFDHHAYRRRVN 104
            :.||:..||.|||.|          |:|:               ||:....        ||....
Zfish    12 IIFYLSIGAAIFQVI----------EEPN---------------WEIAVRK--------YRADKE 43

  Fly   105 DVL----------LDYQRAIVKKQLKGPDV--------EQWSFSGAFLYSLTVITTIGYGNITPH 151
            .:|          |||...:| ....|..:        ..|::..|.:::.|||||||||||.|.
Zfish    44 SILKQYPCLTKADLDYILEVV-SDAAGQGITITGDKTFNNWNWPNAVIFAATVITTIGYGNIAPK 107

  Fly   152 SECGKLVTILYAIIGMPLFLLYLSNIGDVL---AKSFKWIYSKVCLCRICPGVAKRRIIRERRKM 213
            :..|::..|.|.:.|:||...::|.:|...   ||...|..:|       .||..|:
Zfish   108 TPSGRVFCIFYGLFGVPLCFTWISELGKFFGGRAKHLGWYLTK-------KGVTLRK-------- 157

  Fly   214 RQLARALQMHDMENARGSSSYTSTSSTTSSNSSSSEYTRSSRQSSSLVDIQYTESDSDIEREIRG 278
            .||
Zfish   158 TQL-------------------------------------------------------------- 160

  Fly   279 STDEITVPVTVCVFVMVGYILWGALL--------FGRWEDWNYLDGSYFCLISLSSIGFGDLV-- 333
                      .|..|   ::|||.|:        |...|.|.|::|.||..::|::|||||||
Zfish   161 ----------TCTAV---FLLWGVLIHLVIPPFVFMTQEGWTYIEGLYFSFVTLTTIGFGDLVAG 212

  Fly   334 --PGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQEQVVHNIRAIKR 384
              |.....|..|..|||       ::.||:|.:::.||.....||...:|:|:
Zfish   213 VDPNAEYPTLYRYFVEV-------WIYLGLAWLSLFFNWKVRMVVEAHKALKK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	<127..183	CDD:462301	22/58 (38%)
		Ion_trans_2	292..376	CDD:462301	31/95 (33%)
kcnk5a	NP_001032478.2	Ion_trans_2	77..137	CDD:462301	22/59 (37%)
		Ion_trans_2	171..243	CDD:462301	25/78 (32%)