Protein Alignment sand and twk-45

DIOPT Version :9

• Sequence 1: NP_610349.1
• Gene: sand / 35777
• FlyBaseID: FBgn0033257
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001122742.2
• Gene: twk-45 / 190614
• WormBaseID: WBGene00006695
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 99/422 - (23%)
• Similarity: 164/422 - (38%)
• Gaps: 142/422 - (33%)

  Fly    10 RREK-------PAFERFKDHCRHFTAFMFSNVGIILLVTFYIIGGAFIFQSIEI-FEYERLKSE- 65
            ||||       .|:...|...||.|        :|.::..||..|.|:||.:|. .|.|.|:..
 Worm    64 RREKITWFFAWLAYYHHKFGIRHIT--------LISILAAYICLGGFLFQKLESPREIEELQETL 120

  Fly    66 KPHRFIARNFSGECLSRIWELTAENISFFDHHAYRRRVNDVLLDYQRAIVKKQLK---------- 120
            |....|.:|.:.:.:........|:        ..:::.|:|..|.|.:::.:.|
 Worm   121 KSMNEIIKNETMDIIKITLTTNGED--------RNQKLGDLLRAYHRILLETEGKFHGSAWHKSE 177

  Fly   121 GPDVE-QWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKS 184
            ..|:. .|.||.|..||:|:.:|||||.||..:..||.|:::||.||:|:.||.|.:||....|.
 Worm   178 NLDMNLMWYFSSATFYSMTLFSTIGYGTITCQTFWGKTVSMVYASIGLPIMLLVLGDIGVWFQKV 242

  Fly   185 FKWIYSKVCLCRICPGVAKRRIIRERRKMRQLARALQMHDMENARGSSSYTSTSSTTSSNSSSSE 249
            ....|..|.|                                                      :
 Worm   243 MTNAYIFVML------------------------------------------------------K 253

  Fly   250 YTRSSRQSSSLVDIQYTESDSDIEREIRGSTDEITVPVTVCVFVMVGYILWGALLFGRWED---- 310
            |....:||            .:|:|:      |..:|:.:.:.|:..||:...|....::|
 Worm   254 YKSLRKQS------------IEIKRK------ETLLPMWLAMLVVFTYIIICTLTILLFDDNEGD 300

  Fly   311 ---WNYLDGSYFCLISLSSIGFGDLVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMC----- 367
               .|:.|..||..|||::||.||::|.:         ::.|..| .:..|||:|:|::.
 Worm   301 EPGINFFDAFYFTFISLTTIGLGDVMPYN---------IQYSPFL-PLAFLLGLALISIVNTSIY 355

  Fly   368 -------FNL---MQEQV--VHNIRAIKRGFK 387
                   :||   :::|:  :||.|....|::
 Worm   356 STLYQSFYNLIYSLEDQLDRIHNSRRRGAGYR 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	28/60 (47%)
		Ion_trans_2	292..377	CDD:285168	27/108 (25%)
twk-45	NP_001122742.2	Ion_trans_2	<185..241	CDD:285168	27/55 (49%)
		Ion_trans_2	278..354	CDD:285168	24/85 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163748
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950