DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sand and twk-49

DIOPT Version :9

Sequence 1:	NP_610349.1	Gene:	sand / 35777	FlyBaseID:	FBgn0033257	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001022268.1	Gene:	twk-49 / 187626	WormBaseID:	WBGene00019904	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	61/231 - (26%)
Similarity:	95/231 - (41%)	Gaps:	57/231 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSRRSSFRRREKPAFERFKDHCRHFTAFMFSNVGIILLVTFYIIGGAFIFQSIEIFEYERLKSEK 66
            :||.||..|  .|.|:|            :|.|.:|||.|.:|:.||..|     :.:||    .
Worm    31 TSRISSATR--SPCFQR------------WSPVLLILLTTVFILFGATCF-----YLFER----D 72

  Fly    67 PHRFIA-----------RNFSGECLSRIWELTAENISFFDHHAYRRRVNDVLLD-YQRAIVKKQL 119
            ||....           |.|:....|||:..|...:...|.. ...||..:|:: .:|...|..:
Worm    73 PHEMTVRKWYMNLAVERRQFARTISSRIFNDTRNLLIIIDRE-QTERVQQLLVESLKRYEDKLTI 136

  Fly   120 KGPDVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKS 184
            ..|...:||:..:|.::.:::.|||.|...|.:...::..:.|.:||:|||
Worm   137 VPPSRREWSWISSFNFAYSLLLTIGGGFKVPATVGSQIFAVFYCLIGIPLF-------------- 187

  Fly   185 FKWIYSKVCL--CRICPGVAK-RRIIRERRKMRQLA 217
                ||.:.|  ||:...|.| ..:.|.||.:..||
Worm   188 ----YSTLILIVCRLVSPVLKWPSLTRSRRFLLILA 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	14/59 (24%)
sand	NP_610349.1	Ion_trans_2	292..377	CDD:285168
twk-49	NP_001022268.1	Ion_trans_2	<144..191	CDD:369572	16/64 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010