DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sand and XB5727110

DIOPT Version :9

Sequence 1:	NP_610349.1	Gene:	sand / 35777	FlyBaseID:	FBgn0033257	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_031747981.1	Gene:	XB5727110 / 100486031	XenbaseID:	XB-GENE-5727111	Length:	318	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	81/353 - (22%)
Similarity:	141/353 - (39%)	Gaps:	126/353 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IILLVTF--YIIGGAFIFQSIEIFEYERLKSE-KPHRF-IARNFSGECLSRIWELTAENISFFDH 96
            |:|.:.|  |::.||.:||.:|....:..|:: :.||. ..:|::  ||::         ...||
Frog    10 ILLAMAFMVYLLVGALVFQVLEKEAEDTAKTDTERHRLDFLKNYT--CLTK---------EALDH 63

  Fly    97 HAYRRRVNDVLLDYQRAI--VKKQLKGPDVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVT 159
                 .||.:....::.|  ::.|.|... ..|..|.:|.::.||:||||||.::|.:..|::..
Frog    64 -----LVNVITDAVKQGIHPLENQTKNSH-SNWDMSSSFFFAGTVVTTIGYGTLSPRTPGGQIFC 122

  Fly   160 ILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCLCRICPGVAKRRIIRERRKMRQLARALQMHD 224
            :|||:.|:||.::.|..:|.:|        |:||                             |.
Frog   123 VLYALFGIPLNVIVLGRVGKIL--------SRVC-----------------------------HR 150

  Fly   225 MENARGSSSYTSTSSTTSSNSSSSEYTRSSRQSSSLVDIQYTESDSDIEREIRGSTDEITVPVTV 289
            :.                                     ||..:        :|...:....:|:
Frog   151 LG-------------------------------------QYFFN--------KGMKPKKAKVLTI 170

  Fly   290 CVFVMVGYILW---GALLFGRWEDWNYLDGSYFCLISLSSIGFGDLVPG--------DRVITADR 343
            ..|.:.|.|::   ..|||.:.|.|.|.:|.|:..||||:|||||.|.|        .|...|
Frog   171 IFFSVTGIIVFLGLPPLLFTKTEKWTYTEGVYYAFISLSTIGFGDYVVGYGPQHFMPFRGFRA-- 233

  Fly   344 DKVEVSFILCAIYLLLGMAVIAMCFNLM 371
                    |..::::.|::.:::.|||:
Frog   234 --------LVCLWIIFGLSWLSLLFNLL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	22/59 (37%)
sand	NP_610349.1	Ion_trans_2	292..377	CDD:285168	29/91 (32%)
XB5727110	XP_031747981.1	Ion_trans_2	86..146	CDD:400301	22/68 (32%)
XB5727110	XP_031747981.1	Ion_trans_2	178..245	CDD:400301	24/76 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910