DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and HXT5

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	520	Identity:	132/520 - (25%)
Similarity:	224/520 - (43%)	Gaps:	73/520 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PQPNRVELLSAQTDPSQKPRWGNLLLLVA---LATTFGGAV---STGYCIGVINAPSKLMKVWCN 73
            |..:.:|.|..:.|...:.:..:.||.|:   |...|||.|   .||...|.:.....:.:....
Yeast    59 PPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGST 123

  Fly    74 QTLHDTYGSNLSAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLF 138
            :....||.|::..|       .:||:|.:|.|||.:..:...:.:|||...:....::::|.::
Yeast   124 RANGTTYLSDVRTG-------LMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIII- 180

  Fly   139 FFCRAASSVE---MLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQ 200
                ..:|::   ...|||.:.||..|.:|...||.:|||:|..|||||.....:.:|.|:.:|.
Yeast   181 ----QIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGY 241

  Fly   201 VCSLANVFGTEDL-----WH------YALTAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKR 254
            ..:    |||::.     |.      :|.:.:|.:.:.      ..||||::|..| |....|||
Yeast   242 CTN----FGTKNYSNSVQWRVPLGLCFAWSIFMIVGMT------FVPESPRYLVEV-GKIEEAKR 295

  Fly   255 ELQRLRGKDAEE--LIAQEM----AEMEAESNAKVQTSSFCD-VLRDPRLTLPLIIVCCFHGGQQ 312
            .|.| ..|..|:  |:..||    :.:|||..|  .::|:.: |...|::....::.......||
Yeast   296 SLAR-ANKTTEDSPLVTLEMENYQSSIEAERLA--GSASWGELVTGKPQMFRRTLMGMMIQSLQQ 357

  Fly   313 LSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCA---L 374
            |:|.|..|||..:||:..||.  |:....:..|.:|...:....:.:.:..||..:::.|.   .
Yeast   358 LTGDNYFFYYGTTIFQAVGLE--DSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMIC 420

  Fly   375 CSVFLFTIAFVLFY---IDQVS-------WFAIACIVCIMGYIFFYQFGLGPIPYFIGAELFEVA 429
            |.|...::.....:   .||.|       ....||.     |||.:.....|:.|.:.:|.:.:.
Yeast   421 CYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACF-----YIFCFATTWAPVAYVLISESYPLR 480

  Fly   430 PRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLFLLTKFYLPETRGRDPSEV 494
            .|..|||:.|..:|...|:|....|.:.:|...:....|....|..:....|::|||:|....||
Yeast   481 VRGKAMSIASACNWIWGFLISFFTPFITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEV 545

Fly 495 494
Yeast 546 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	119/474 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	106/419 (25%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	125/490 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840