DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and HXT17

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_014470.1	Gene:	HXT17 / 855809	SGDID:	S000005355	Length:	564	Species:	Saccharomyces cerevisiae

Alignment Length:	515	Identity:	137/515 - (26%)
Similarity:	232/515 - (45%)	Gaps:	72/515 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPSQKPRWGNLLL-LVALATTFGGAV---STGYCIGVINAPSKLMKVWCNQTLHDT---YGSNLS 85
            :|.::...|.|:: |:....:|||.:   .:|...|.||..:  .|:......|.|   |.||:.
Yeast    45 EPPKRGLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDN--FKMNFGSYKHSTGEYYLSNVR 107

  Fly    86 AGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVE-- 148
            .|       .:|::|.:|.|||.|..|..|:..||:...:|...::.|||::    :.:|:.:
Yeast   108 MG-------LLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAII----QISSNHKWY 161

  Fly   149 MLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDL 213
            ...:|:.:.||.:|..:...||.|||:||..|||.|.....:.:|.|:.:| .||   |:||...
Yeast   162 QYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLG-YCS---VYGTRKY 222

  Fly   214 -----WHYALTAYMFLILVCYLPSYLFPESPKFLYIVKGNR-AAAKRELQRLRG---------KD 263
                 |...|.......|:..:...|.||||:  |:::..| ..|:..:.::..         |.
Yeast   223 DNTAQWRVPLGLCFLWTLIIIIGMLLVPESPR--YLIECERHEEARASIAKINKVSPEDPWVLKQ 285

  Fly   264 AEELIAQEMAEME-AESNAKVQTSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIF 327
            |:|:.|..:|:.| .|::.|...|....||:  ||...:::....    ||:|.|..|:|..:||
Yeast   286 ADEINAGVLAQRELGEASWKELFSVKTKVLQ--RLITGILVQTFL----QLTGENYFFFYGTTIF 344

  Fly   328 EKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCA---LCSVFLFTIAFVLFY- 388
            :..||:  |....::..|.:|...:::...::.|..||..::|..|   .|.|...:|.....|
Yeast   345 KSVGLT--DGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYP 407

  Fly   389 ------IDQVSWFAIACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNF 447
                  ..:.:..|:....|.  |||.:.....|:.|.:.||.|....:|.|||:.:..:|...|
Yeast   408 HGQDGPSSKGAGNAMIVFTCF--YIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQF 470

  Fly   448 IIGISFPLLQNA---WGAFVFLPFSITC-VLLFLLTKFYLPETRGRDPSEVAPLVSKGFR 503
            :||...|.:..:   :..:||    :.| |.:||...|:||||.|....|:..|..:|.:
Yeast   471 LIGFFTPFITGSIHFYYGYVF----VGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIK 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	128/476 (27%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	110/417 (26%)
HXT17	NP_014470.1	Sugar_tr	60..521	CDD:395036	131/493 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840