DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and HXT14

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_014081.1	Gene:	HXT14 / 855398	SGDID:	S000005262	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	490	Identity:	118/490 - (24%)
Similarity:	230/490 - (46%)	Gaps:	52/490 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LLVALATTFGGAVSTGYCIGVINAPSKLM----KVWCNQTLHDTYGSNLSAGGL-DLLWSCVVSV 99
            :|:.|..:.||.: .|:.||.|...:.::    |......:||.....:|...| ||....::|:
Yeast    61 VLLCLVISLGGFI-FGWDIGTIGGMTNMVSFQEKFGTTNIIHDDETIFVSTKKLTDLQIGLIISI 124

  Fly   100 FLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVL-------FFFCRAASSVEMLVIGRFVV 157
            |.:...:|:|..:...:..|||........::.:|..:       ::|         |.:||.|.
Yeast   125 FNISCGVGALTLSKIGDWIGRKGGIWFALVVYCIGITIQILSYGRWYF---------LTLGRAVT 180

  Fly   158 GLASGLVTATLPMYLSEVAPMALRG----TLGVFIAVGVTGGVVVGQVCSLANVFGTEDL-WHYA 217
            |:..|:.|..:||:|||.:|:.:||    |..:.:..|:..|.::..:|.......|::: |...
Yeast   181 GIGVGVTTVLVPMFLSENSPLKIRGSMVSTYQLIVTFGILMGNILNFICERCYKDPTQNIAWQLP 245

  Fly   218 L-TAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIA------------ 269
            | ..|::.|::.....|: ||||::|..:|.:..:||....|:.|..|.:.:.
Yeast   246 LFLGYIWAIIIGMSLVYV-PESPQYLAKIKNDVPSAKYSFARMNGIPATDSMVIEFIDDLLENNY 309

  Fly   270 -QEMAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLS 333
             .|....|::..:.|:.::|..::..|:|.|.|||.......|||||||..|||..|:|:..|:.
Yeast   310 NNEETNNESKKQSLVKRNTFEFIMGKPKLWLRLIIGMMIMAFQQLSGINYFFYYGTSVFKGVGIK 374

  Fly   334 TVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIA 398
              |....::....:|...::||.:.:.|...:|.:::.......::.|.|.|..:..:..:..|.
Yeast   375 --DPYITSIILSSVNFLSTILGIYYVEKWGHKTCLLYGSTNLLFYMMTYATVGTFGRETDFSNIV 437

  Fly   399 CIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWG-- 461
            .|:....:||::...|||:.:.:.:|||.:..|:::|::.:..:|..||:|.:..|::.:...
Yeast   438 LIIVTCCFIFWFAITLGPVTFVLVSELFPLRTRAISMAICTFINWMFNFLISLLTPMIVSKIDFK 502

  Fly   462 -AFVFLPFSITCVLLFLLTKFYL-PETRGRDPSEV 494
             .::|    ..|:|..::..:.| ||||.::..|:
Yeast   503 LGYIF----AACLLALIIFSWILVPETRKKNEQEI 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	114/475 (24%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	97/414 (23%)
HXT14	NP_014081.1	MFS_HXT	62..537	CDD:340914	118/489 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I1110
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960