DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and HXT16

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_012692.3	Gene:	HXT16 / 853623	SGDID:	S000003919	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	558	Identity:	141/558 - (25%)
Similarity:	241/558 - (43%)	Gaps:	95/558 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AQQLYPQPNRVELLSAQTD----PSQKPRW-----------GN-------------LLLLVALAT 46
            ::|..|:.|...|.|:..|    |..:..|           ||             ::.|:....
Yeast     3 SEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPKRGFLGYLIIYLLCYPV 67

  Fly    47 TFGGAV---STGYCIGVINAPSKLMKVWCNQTLHDT---YGSNLSAGGLDLLWSCVVSVFLVGGA 105
            :|||.:   .:|...|.||..:  .|:......|.|   |.||:..|       .:|::|.||.:
Yeast    68 SFGGFLPGWDSGITAGFINMDN--FKMNFGSYKHSTGEYYLSNVRMG-------LLVAMFSVGCS 123

  Fly   106 IGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVE--MLVIGRFVVGLASGLVTATL 168
            ||.:..|..|:..||:...:|...::.|||::    :.:|:.:  ...:|:.:.||.:|..:...
Yeast   124 IGGVAFARLADTLGRRLAIVIVVLVYMVGAII----QISSNHKWYQYFVGKIIYGLGAGGCSVLC 184

  Fly   169 PMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDL-----WHYALTAYMFLILVC 228
            ||.|||:||..|||.|.....:.:|.|:.:| .||   |:||...     |...:.......|:.
Yeast   185 PMLLSEIAPTDLRGGLVSLYQLNMTFGIFLG-YCS---VYGTRKYSNTAQWRIPVGLCFLWALII 245

  Fly   229 YLPSYLFPESPKFLYIVKGNRAA--AKRELQRLRGKD------AEELIAQEMAEME-AESNAKVQ 284
            .:...|.||||::|...:.:..|  :..::.::..:|      |:|:.|..:|:.| .|::.|..
Yeast   246 IVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKEL 310

  Fly   285 TSSFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNL 349
            .|....||:  ||...:::....    ||:|.|..|:|..:||:..||:  |....::..|.:|.
Yeast   311 FSVKTKVLQ--RLITGILVQTFL----QLTGENYFFFYGTTIFKSVGLT--DGFETSIVLGTVNF 367

  Fly   350 AVSLLGPWLMAKCNRRTLMMFSCA---LCSVFLFTIAFVLFY-------IDQVSWFAIACIVCIM 404
            ..:::...::.|..||..::|..|   .|.|...:|.....|       ..:.:..|:....|.
Yeast   368 FSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCF- 431

  Fly   405 GYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNA---WGAFVFL 466
             |||.:.....|:.|.:.||.|....:|.|||:.:..:|...|:||...|.:..:   :..:||
Yeast   432 -YIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVF- 494

  Fly   467 PFSITC-VLLFLLTKFYLPETRGRDPSEVAPLVSKGFR 503
               :.| |.:||...|:||||.|....|...|..:|.:
Yeast   495 ---VGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	125/474 (26%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	107/415 (26%)
HXT16	NP_012692.3	Sugar_tr	63..524	CDD:278511	128/491 (26%)
HXT16	NP_012692.3	MFS	67..510	CDD:119392	122/473 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342883
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840