DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and MAL11

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	489	Identity:	119/489 - (24%)
Similarity:	185/489 - (37%)	Gaps:	105/489 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LWSCVVSVFLV------------------GGAIGSLGGAGAAN-----KFGRKACFLICG----- 128
            |||.:||..||                  ....|:|.|.|:..     :.|...| ::||
Yeast   108 LWSILVSTTLVMEGYDTALLSALYALPVFQRKFGTLNGEGSYEITSQWQIGLNMC-VLCGEMIGL 171

  Fly   129 --------------------ALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLPMYLS 173
                                .|.|....:.::|:   |:.|:.:|:.:..:..|...:....|.|
Yeast   172 QITTYMVEFMGNRYTMITALGLLTAYIFILYYCK---SLAMIAVGQILSAIPWGCFQSLAVTYAS 233

  Fly   174 EVAPMALR----------GTLGVFIAVGVTGGVVVGQVCSLAN-------VFGTEDLWHYALTAY 221
            ||.|:|||          ...|...|    .|::.....:|.|       .|..:.:|...|...
Yeast   234 EVCPLALRYYMTSYSNICWLFGQIFA----SGIMKNSQENLGNSDLGYKLPFALQWIWPAPLMIG 294

  Fly   222 MFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQR-LRGKDAEELIAQEMA------EMEAES 279
            :|..          ||||.:| :.|...|.|::.|.| |.||.||:.|..::.      .:|.|.
Yeast   295 IFFA----------PESPWWL-VRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQIELTIEKER 348

  Fly   280 NAKVQTSSFCDVLR--DPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANL 342
            ....::.||.:..:  :.|.|.   :.|.....|..||. .:..||...||:||::|..|...:|
Yeast   349 LLASKSGSFFNCFKGVNGRRTR---LACLTWVAQNSSGA-VLLGYSTYFFERAGMATDKAFTFSL 409

  Fly   343 GAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYI 407
            ...||.||.:|....:..:..|.|::.:..|...|.||.|..:.|  ...|..:......::...
Yeast   410 IQYCLGLAGTLCSWVISGRVGRWTILTYGLAFQMVCLFIIGGMGF--GSGSSASNGAGGLLLALS 472

  Fly   408 FFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNA----WGAFVFLPF 468
            |||..|:|.:.|.|.||:.....|:..:.:..:.......|..|..|.:.|.    |||...|.:
Yeast   473 FFYNAGIGAVVYCIVAEIPSAELRTKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTGLYW 537

  Fly   469 -SITCVLLFLLTKFYLPETRGRDPSEVAPLVSKG 501
             ..|.|.|..:. ..||||.||..||:..|.::|
Yeast   538 GGFTAVTLAWVI-IDLPETTGRTFSEINELFNQG 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	117/483 (24%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	106/464 (23%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	116/480 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342811
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840