DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and STL1

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_010825.3	Gene:	STL1 / 852149	SGDID:	S000002944	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	463	Identity:	115/463 - (24%)
Similarity:	197/463 - (42%)	Gaps:	78/463 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 HDTYGSNLSAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFC 141
            ||.:.:        ::.....|.:.:|...|||.......:.|||...|:...:..:|||: ..|
Yeast    71 HDRHAT--------VVQGATTSCYELGCFAGSLFVMFCGERIGRKPLILMGSVITIIGAVI-STC 126

  Fly   142 --RAASSVEMLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTL----------GVFIAVGVTG 194
              |...::...:|||.|.|:.:||.|:|:|::.||::....||.|          |..||..:..
Yeast   127 AFRGYWALGQFIIGRVVTGVGTGLNTSTIPVWQSEMSKAENRGLLVNLEGSTIAFGTMIAYWIDF 191

  Fly   195 GVVVGQVCSLANVFGTEDLWHYALTAYMFLILVCYLPSYL--FPESPKFLYIVKGNRAAAKRELQ 257
            |:      |..|   :...|.:.::  |.::...:|.:::  .||||::| |.:.....|:..:.
Yeast   192 GL------SYTN---SSVQWRFPVS--MQIVFALFLLAFMIKLPESPRWL-ISQSRTEEARYLVG 244

  Fly   258 RLRGKDA--EELIAQEMAEMEAESNAKVQTSSFCDVL---RDPRLTLPLIIVCC-FHGGQQLSGI 316
            .|...|.  ||:|.:.....:|.:..|.:..|...:.   |...|...||.... |.  ||.:|.
Yeast   245 TLDDADPNDEEVITEVAMLHDAVNRTKHEKHSLSSLFSRGRSQNLQRALIAASTQFF--QQFTGC 307

  Fly   317 NAIFYYSVSIFEKAGLSTVDAQWANL--GAGCLNLAVSLLGP-WLMAKCNRRTLMMFSCALCSVF 378
            ||..|||..:|.|.  ..:|.:.:.:  |......|:|.:|. :|:.|..||.|.:.. |.....
Yeast   308 NAAIYYSTVLFNKT--IKLDYRLSMIIGGVFATIYALSTIGSFFLIEKLGRRKLFLLG-ATGQAV 369

  Fly   379 LFTIAFVLFYIDQVSWFAIACIV---------CIMG-YIFFYQFGLG--PIPYFIGAELFEVAPR 431
            .|||.|             ||:|         ..:| ::|...|||.  .:|:....|:..:..|
Yeast   370 SFTITF-------------ACLVKENKENARGAAVGLFLFITFFGLSLLSLPWIYPPEIASMKVR 421

  Fly   432 SVAMSMGSLASWTCNFIIGISFPLL--QNAWGAFVFLPFSITCVLLFLLTKFYLPETRGRDPSEV 494
            :...:..:..:|.|||.:.:..|:.  |:.||.::|  |::...|...:..|:.|||.||...|:
Yeast   422 ASTNAFSTCTNWLCNFAVVMFTPIFIGQSGWGCYLF--FAVMNYLYIPVIFFFYPETAGRSLEEI 484

  Fly   495 APLVSKGF 502
            ..:.:|.:
Yeast   485 DIIFAKAY 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	114/456 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	105/422 (25%)
STL1	NP_010825.3	Sugar_tr	32..488	CDD:395036	114/457 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910