DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and HXT3

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_010632.1	Gene:	HXT3 / 851946	SGDID:	S000002753	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	532	Identity:	128/532 - (24%)
Similarity:	212/532 - (39%)	Gaps:	84/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AEAQQLYPQPNRVELLSAQTDPSQKPRWGNLLLLVALATTFGGAV---STGYCIGVINAPSKLMK 69
            |||.|:...||..:  .|....|          :..:...|||.|   .||...|.:.....|.:
Yeast    43 AEADQVLTNPNTGK--GAYVTVS----------ICCVMVAFGGFVFGWDTGTISGFVAQTDFLRR 95

  Fly    70 VWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVG 134
            ..........|.|.:..|       .:||:|.:|.|||.:..|...:.:|||...::...::.:|
Yeast    96 FGMKHKDGSYYLSKVRTG-------LIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIG 153

  Fly   135 AVLFFFCRAASSVE---MLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGV 196
            .::     ..:|:.   ...|||.:.||..|.:....||.:|||||..:||||.....:.:|.|:
Yeast   154 III-----QIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGI 213

  Fly   197 VVGQVCSLANVFGTEDL-----WHYALTAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKREL 256
            .:|...:    |||::.     |...|.......|.........||||::| :..|....|:..|
Yeast   214 FLGYCTN----FGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYL-VEAGQIDEARASL 273

  Fly   257 QRLRGKDAEE--LIAQEMAEMEA--ESNAKVQTSSFCDVLR-DPRLTLPLIIVCCFHGGQQLSGI 316
            .:: .|.|.:  .|.||:..:||  |......::|:.::.. .|.:....::.......|||:|.
Yeast   274 SKV-NKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGD 337

  Fly   317 NAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFT 381
            |..|||..::|...|:|  |:...::..|.:|...:....:.:.:..||..:::.         .
Yeast   338 NYFFYYGTTVFNAVGMS--DSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYG---------A 391

  Fly   382 IAFVLFYIDQVS------W----------------FAIACIVCIMGYIFFYQFGLGPIPYFIGAE 424
            |..|..|:...|      |                ...||.     |||.:.....||.|.:.:|
Yeast   392 IGMVCCYVVYASVGVTRLWPNGEGNGSSKGAGNCMIVFACF-----YIFCFATTWAPIAYVVISE 451

  Fly   425 LFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLFLLTKFYLPETRGR 489
            .|.:..:|.|||:.:.|:|...|:||...|.:..|...:....|....|..:....|::|||:|.
Yeast   452 TFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGL 516

  Fly   490 DPSEVAPLVSKG 501
            ...||..:.::|
Yeast   517 TLEEVNDMYAEG 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	114/476 (24%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	101/420 (24%)
HXT3	NP_010632.1	Sugar_tr	65..525	CDD:395036	119/493 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840