DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and SNF3

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	504	Identity:	120/504 - (23%)
Similarity:	225/504 - (44%)	Gaps:	61/504 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TDPSQKPRWGNLLLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCN-QTLHDTYGSNLSAGGLD 90
            ::|.||... .:.:.|.:....||.: .||..|:||:.:.:..|..: ...||::.:.
Yeast    86 SEPPQKQSM-MMSICVGVFVAVGGFL-FGYDTGLINSITSMNYVKSHVAPNHDSFTAQ------- 141

  Fly    91 LLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGA-LFTVGAVLFFFCRAASSVEMLVIGR 154
             ..|.:||...:|...|:|.....::.:|||...:.... :|::|..|..   .|..:.:|::||
Yeast   142 -QMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSLQV---GAGGITLLIVGR 202

  Fly   155 FVVGLASGLVTATLPMYLSEVAPMALRG----------TLGVFIAVGVTGGVVVGQVCSLANV-F 208
            .:.|:..|.::|.:|:|.:|....:|||          |.|:.::..|:.|.......|...: .
Yeast   203 VISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPI 267

  Fly   209 GTEDLWHYALTAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEEL-IAQEM 272
            |.:.:|...|...||.:          ||||:: |::|.....|.:.|..|||....:. :.:|:
Yeast   268 GLQYVWSSFLAIGMFFL----------PESPRY-YVLKDKLDEAAKSLSFLRGVPVHDSGLLEEL 321

  Fly   273 AEMEA--ESNAKVQTSSFCDVL----RDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAG 331
            .|::|  :..|...:|:|.|..    ..|:.||.:.........||.||||.||||.|:.|.|.|
Yeast   322 VEIKATYDYEASFGSSNFIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTG 386

  Fly   332 LSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMFSCALCSVFLFTIAFVLFYIDQVSWFA 396
            :|  ::...:.....:|:..::.|.:.:....||.:::....:.::..|.:|.|...:..|:...
Yeast   387 VS--NSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIVGCSLKTVAAAK 449

  Fly   397 I-ACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLL---- 456
            : ...:|:  :|..:....|.:.:.|.|||:.:..||...::.:.|:|..|||..:..|.:
Yeast   450 VMIAFICL--FIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTG 512

  Fly   457 --QNAWGA---FVFLPFSITCVLLFLLTKFYLPETRGRDPSEVAPLVSK 500
              .::.||   |::...:...|::..||.:   ||:|....|:..|..|
Yeast   513 SHTSSLGAKIFFIWGSLNAMGVIVVYLTVY---ETKGLTLEEIDELYIK 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	112/471 (24%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	99/414 (24%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	115/486 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840