DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut1 and HXT10

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	531	Identity:	134/531 - (25%)
Similarity:	230/531 - (43%)	Gaps:	87/531 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ELLSAQTDPSQKP---RWG--NLLLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTY 80
            |...|..|...||   .|.  .|.|::|    |||.: .|:..|.|:.       :.|||.....
Yeast    30 ETREASLDIPYKPIIAYWTVMGLCLMIA----FGGFI-FGWDTGTISG-------FINQTDFKRR 82

  Fly    81 GSNLSAGG----LDLLWSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFC 141
            ...|...|    .|:....:|.:|.:|.|:|.|......:.:|||...:....::.||.|:
Yeast    83 FGELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVI---- 143

  Fly   142 RAASSVE--MLVIGRFVVGLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSL 204
            :.|||.:  ...|||.|.|:..|.|....|..:||::|..||||...|..:.:|.|:.:|...:
Yeast   144 QIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTN- 207

  Fly   205 ANVFGTEDL-----WH------YALTAYMFLILVCYLPSYLFPESPKFLYIVKGNRAAAKRELQR 258
               :||:..     |.      :|...:|.:.:|      :.||||::| :.||....|:|.|
Yeast   208 ---YGTKKYSNSIQWRVPLGLCFAWAIFMVIGMV------MVPESPRYL-VEKGKYEEARRSL-- 260

  Fly   259 LRGKDAEELIAQE---------MAEMEAESNAKVQTSSFCDVLRDPRLTLPLIIV-CCFHGGQQL 313
              .|..:..:...         :|.||.|  ..|..:|:.::..:....||.:|: ......|||
Yeast   261 --AKSNKVTVTDPGVVFEFDTIVANMELE--RAVGNASWHELFSNKGAILPRVIMGIVIQSLQQL 321

  Fly   314 SGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMAKCNRRTLMMF---SCALC 375
            :|.|..|||..:||...|:.  |:...::..|.:|.|.:.:..:::.|..||..:::   |.|:|
Yeast   322 TGCNYFFYYGTTIFNAVGMQ--DSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAIC 384

  Fly   376 SVFLFTIAFVLFY---IDQVSWFAIACIVCIMGYIFFYQFGL--GPIPYFIGAELFEVAPRSVAM 435
            .|...|:.....:   .||.|..:...::.:....|.:.|.:  .||.|.|.||.:.:..::.||
Yeast   385 FVIFATVGVTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAM 449

  Fly   436 SMGSLASWTCNFIIGISFPLLQNAWG---AFVFLPFSITCVLL-FLLTKFYLPETRGRDPSEVAP 496
            ::...|:|...|:||...|.:..:.|   .:||:    .|::. :....|::.||:|....|
Yeast   450 AIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFM----GCLIFSYFYVFFFVCETKGLTLEE--- 507

  Fly   497 LVSKGFRSKVK 507
             |::.:..::|
Yeast   508 -VNEMYEERIK 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	120/480 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	106/420 (25%)
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	127/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840