DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and INT4

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001328028.1	Gene:	INT4 / 827346	AraportID:	AT4G16480	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	145/566 - (25%)
Similarity:	231/566 - (40%)	Gaps:	128/566 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVG 103
            ::.:||:...||.: .||..|||:.....:|...::....|:           |.|.:||:.:.|
plant    27 IMRLALSAGIGGLL-FGYDTGVISGALLFIKEDFDEVDKKTW-----------LQSTIVSMAVAG 79

  Fly   104 GAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATL 168
            ..:|:..|....:||||:...||...||.:||::..|   |.:..::::||..||...|:.:.|.
plant    80 AIVGAAVGGWINDKFGRRMSILIADVLFLIGAIVMAF---APAPWVIIVGRIFVGFGVGMASMTS 141

  Fly   169 PMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFLILVCYLPSY 233
            |:|:||.:|..:||.|.....:.:|||.....:.:||.|. |...|.:.|.......:|.::...
plant   142 PLYISEASPARIRGALVSTNGLLITGGQFFSYLINLAFVH-TPGTWRWMLGVAGVPAIVQFVLML 205

  Fly   234 LFPESPKFLYIVKGNRAAAKRE-LQRLRGKDAEELIAQEMAEMEA--------ESNAKVQTSSFC 289
            ..||||::||  :.:|.|..|. |:|:...|..|      |||||        :::..:...||.
plant   206 SLPESPRWLY--RKDRIAESRAILERIYPADEVE------AEMEALKLSVEAEKADEAIIGDSFS 262

  Fly   290 DVLR----DPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAG-LSTVDAQWANLGAGCLNL 349
            ..|:    :|.:...|.........||..|||.:.|||.||.:.|| .|...|...:|....||.
plant   263 AKLKGAFGNPVVRRGLAAGITVQVAQQFVGINTVMYYSPSIVQFAGYASNKTAMALSLITSGLNA 327

  Fly   350 AVSLLGPWLMAKCNRRTLM---MFSCALCSVFLFTI------------AF--------------- 384
            ..|::....:.:..||.||   ||....|.:.|.|:            ||
plant   328 LGSIVSMMFVDRYGRRKLMIISMFGIIACLIILATVFSQAAIHAPKIDAFESRTFAPNATCSAYA 392

  Fly   385 --------------------------------------VL--------------FYIDQV-SWFA 396
                                                  ||              |:.|.. |.|.
plant   393 PLAAENAPPSRWNCMKCLRSECGFCASGVQPYAPGACVVLSDDMKATCSSRGRTFFKDGCPSKFG 457

  Fly   397 IACIVCIMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWG 461
            ...||.:..||..|..|:|.:|:.:.:|::.:..|.:...:.::::|..|.|:..||..|.:|.|
plant   458 FLAIVFLGLYIVVYAPGMGTVPWIVNSEIYPLRYRGLGGGIAAVSNWVSNLIVSESFLSLTHALG 522

  Fly   462 A----FVFLPFSITCVLLFLLTKFYLPETRGRDPSEVAPLVSKGFR 503
            :    .:|..|| |..|.|:.  ..:|||:|....||..|:..||:
plant   523 SSGTFLLFAGFS-TIGLFFIW--LLVPETKGLQFEEVEKLLEVGFK 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	138/542 (25%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	123/486 (25%)
INT4	NP_001328028.1	MFS_HMIT_like	33..547	CDD:340918	134/540 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920