Protein Alignment sut1 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_523658.1
• Gene: sut1 / 35774
• FlyBaseID: FBgn0028563
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 186/491 - (37%)
• Similarity: 279/491 - (56%)
• Gaps: 39/491 - (7%)

  Fly    28 DPSQKPRWGNLLLLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLL 92
            :||.|...|.|:|.|..|..  |::..||..||||||.|:::.:.|||....||.::....|..|
Human     2 EPSSKKLTGRLMLAVGGAVL--GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64

  Fly    93 WSCVVSVFLVGGAIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVV 157
            ||..|::|.|||.|||.......|:|||:...|:...|..|.|||..|.:...|.|||::|||::
Human    65 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129

  Fly   158 GLASGLVTATLPMYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYM 222
            |:..||.|..:|||:.||:|.||||.||....:|:..|:::.||..|.::.|.:|||       .
Human   130 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLW-------P 187

  Fly   223 FLILVCYLPSYL-------FPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAESN 280
            .|:.:.::|:.|       .||||:||.|.:.....||..|::||| .|:  :..::.||:.||.
Human   188 LLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRG-TAD--VTHDLQEMKEESR 249

  Fly   281 AKVQTS--SFCDVLRDPRLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLG 343
            ..::..  :..::.|.|....|::|.......||||||||:||||.|||||||:.  ...:|.:|
Human   250 QMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ--QPVYATIG 312

  Fly   344 AGCLNLAVSLLGPWLMAKCNRRTLM------MFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVC 402
            :|.:|.|.:::..:::.:..||||.      |..||:    |.|||..|  ::|:.|.:...||.
Human   313 SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI----LMTIALAL--LEQLPWMSYLSIVA 371

  Fly   403 IMGYIFFYQFGLGPIPYFIGAELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLP 467
            |.|::.|::.|.||||:||.||||...||..|:::...::||.|||:|:.|..::...|.:||:.
Human   372 IFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFII 436

  Fly   468 FSITCVLLFLLTKFYLPETRGRDPSEVAPLVSKGFR 503
            |::..||.|:.|.|.:|||:||...|:|    .|||
Human   437 FTVLLVLFFIFTYFKVPETKGRTFDEIA----SGFR 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	174/456 (38%)
		MFS	96..482	CDD:119392	148/400 (37%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	174/463 (38%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		5/5 (100%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	0.197	Inparanoid score	I2535
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.900