DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut1 and slc2a1a

DIOPT Version :9

Sequence 1:	NP_523658.1	Gene:	sut1 / 35774	FlyBaseID:	FBgn0028563	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001034897.1	Gene:	slc2a1a / 555778	ZFINID:	ZDB-GENE-030131-3158	Length:	488	Species:	Danio rerio

Alignment Length:	472	Identity:	173/472 - (36%)
Similarity:	270/472 - (57%)	Gaps:	21/472 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LLVALATTFGGAVSTGYCIGVINAPSKLMKVWCNQTLHDTYGSNLSAGGLDLLWSCVVSVFLVGG 104
            |::|:.|...|::..||..||||||.|:::.:.|:|.|:.|...:....|..|||..|::|.|||
Zfish    12 LMMAVGTAVIGSLQFGYNTGVINAPQKIIEGFYNETWHNRYSEYIPPTTLTTLWSVSVAIFSVGG 76

  Fly   105 AIGSLGGAGAANKFGRKACFLICGALFTVGAVLFFFCRAASSVEMLVIGRFVVGLASGLVTATLP 169
            .:||.......|:|||:...||...|..:.|....|.:.|.|.|||:||||:|||.|||.|..:|
Zfish    77 ILGSFSVGLFVNRFGRRNSMLIANILAFIAAAFMGFSKLAESWEMLIIGRFIVGLYSGLSTGFVP 141

  Fly   170 MYLSEVAPMALRGTLGVFIAVGVTGGVVVGQVCSLANVFGTEDLWHYALTAYMFL--ILVCYLPS 232
            ||:.|:||.:|||.||....:|:..|:::.|:..:..:.|:..||.:.| .:.|:  :|.|.|..
Zfish   142 MYVGEIAPTSLRGALGTLHQLGIVIGILMAQIFGIKEIMGSPTLWPFML-GFTFIPAVLQCALLP 205

  Fly   233 YLFPESPKFLYIVKGNRAAAKRELQRLRGKDAEELIAQEMAEMEAESN--AKVQTSSFCDVLRDP 295
            :. ||||::|.|.:...|.||..|::|||.|.   :..:|.||..||.  .:.:|.:..::.|..
Zfish   206 FC-PESPRYLLINQNEEAKAKSVLKKLRGTDD---VGADMQEMRDESRQMMREKTVTIPELFRSS 266

  Fly   296 RLTLPLIIVCCFHGGQQLSGINAIFYYSVSIFEKAGLSTVDAQWANLGAGCLNLAVSLLGPWLMA 360
            ....|:.|.......||.|||||:||||..||||||:|  :..:|.:|||.:|.|.:::..:::.
Zfish   267 LYRQPIFIAIMLQLSQQFSGINAVFYYSTGIFEKAGVS--EPVYATIGAGAVNTAFTVVSLFIVE 329

  Fly   361 KCNRRTLM---MFSCALCSVFLFTIAFVLFYIDQVSWFAIACIVCIMGYIFFYQFGLGPIPYFIG 422
            :..||:|.   :...|:.|| |.|||..|  :.:|.|.:...||.|..::.|::.|.||||:||.
Zfish   330 RVGRRSLHLVGLMGMAVSSV-LMTIAMAL--LTKVEWMSYVSIVAIFSFVAFFEIGPGPIPWFIV 391

  Fly   423 AELFEVAPRSVAMSMGSLASWTCNFIIGISFPLLQNAWGAFVFLPFSITCVLLFLLTKFYLPETR 487
            ||||...||..|.::...::|..||::|:.|..::...|.:||:.|::..::.|:.|.|.:|||:
Zfish   392 AELFSQGPRPSAFAVAGFSNWFANFLVGMCFQYVEELTGPYVFIIFTVLLLIFFVFTYFKVPETK 456

  Fly   488 GRDPSEVAPLVSKGFRS 504
            ||...|    ::..||:
Zfish   457 GRSFEE----ITASFRT 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut1	NP_523658.1	Sugar_tr	55..497	CDD:278511	167/448 (37%)
sut1	NP_523658.1	MFS	96..482	CDD:119392	143/392 (36%)
slc2a1a	NP_001034897.1	Sugar_tr	18..467	CDD:278511	169/462 (37%)
slc2a1a	NP_001034897.1	MFS	62..450	CDD:119392	146/397 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900